以卒中样发作为首发症状的线粒体脑肌病1例

王春阳, 张琳, 梁雅靖, 赵凤丽

承德医学院学报 ›› 2026, Vol. 43 ›› Issue (5) : 429 -431.

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承德医学院学报 ›› 2026, Vol. 43 ›› Issue (5) : 429 -431.
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以卒中样发作为首发症状的线粒体脑肌病1例

    王春阳1, 张琳2, 梁雅靖3, 赵凤丽2,*
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线粒体脑肌病 / MELAS综合征 / 卒中样发作 / m.3243A>G突变 / 磁共振成像

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王春阳, 张琳, 梁雅靖, 赵凤丽. 以卒中样发作为首发症状的线粒体脑肌病1例[J]. 承德医学院学报, 2026, 43(5): 429-431 DOI:

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参考文献

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[4] Tetsuka S, Ogawa T, Hashimoto R, et al.Clinical features, pathogenesis, and management of stroke-like episodes due to MELAS[J]. Metab Brain Dis, 2021, 36(8): 2181-2193.
[5] Gagliardi D, Mauri E, Magri F, et al.Can Intestinal Pseudo-Obstruction Drive Recurrent Stroke-Like Episodes in Late-Onset MELAS Syndrome? A Case Report and Review of the Literature[J]. Front Neurol, 2019, 10: 38.
[6] Li J, Zhang W, Cui Z, et al.Epilepsy Associated With Mitochondrial Encephalomyopathy, Lactic Acidosis, and Stroke-Like Episodes[J]. Front Neurol, 2021, 12: 675816.
[7] Rahman S.Mitochondrial disease in children[J]. J Intern Med, 2020, 287(6): 609-633.
[8] 赵静,王训,程楠,等. 线粒体脑肌病伴乳酸血症和卒中样发作综合征的临床、EEG、影像学及肌肉病理特点分析[J]. 临床神经病学杂志,2021,34(2):121-126.
[9] Li X, Wang Y, Wang Z, et al.Comparison of magnetic resonance spectroscopy (MRS) with arterial spin labeling (ASL) in the differentiation between mitochondrial encephalomyopathy, lactic Acidosis, plus stroke-like episodes (MELAS) and acute ischemic stroke (AIS)[J]. J Clin Neurosci, 2018, 55: 65-70.
[10] Rodriguez M C, MacDonald J R, Mahoney D J, et al. Beneficial effects of creatine, CoQ10, and lipoic acid in mitochondrial disorders[J]. Muscle Nerve, 2007, 35(2): 235-242.
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