难治性癫痫的外科治疗进展

Advances in surgical treatment of refractory epilepsy

摘要

在癫痫患者中，药物难治性癫痫一直占据相当比例。这部分患者在经过精确的评估后或可通过外科治疗的手段达到发作缓解。本文阐述了难治性癫痫的术前神经电生理和影像评估方法，并结合最新临床研究进展，针对不同类型癫痫总结手术治疗方案，补充阐述了无创治疗方法，且在此基础上探讨了癫痫外科治疗未来发展趋势。

Abstract

Medically refractory epilepsy has always affected a considerable proportion of patients with epilepsy. This group of patients may be able to achieve seizure remission by means of surgical treatment after precise evaluation. This article presents preoperative neurophysiological and imaging evaluation methods for refractory epilepsy，and summarizes surgical options for different types of epilepsy in the light of new clinical research advances. We also have a discussion on non-invasive treatments as well as related future trend in surgical treatment for epilepsy.

关键词

难治性癫痫 / 神经诊断技术 / 神经外科手术

Key words

refractory epilepsy / neurological diagnostic technique / neurosurgical procedure

基金资助

国家重点研发计划资助项目(2022YFB4702705)

国家自然科学基金资助项目(82101546)