基于USSQ问卷的患者报告结局和临床干预对改善上尿路结石患者生活质量的研究

Effectiveness of outcome self-reporting and clinical intervention based on USSQ for improving the quality of life of patients with upper urinary tract stones

摘要

目的 探讨基于输尿管支架相关症状问卷（the ureteral stent-related symptom questionnaire，USSQ）的患者报告结局和临床干预对改善上尿路结石患者生活质量的可行性。 方法 招募了2023年6月至2024年6月于重庆医科大学附属第一医院泌尿外科行输尿管支架置入术的上尿路结石患者106例，通过USSQ问卷进行远程的患者自我报告和临床干预，以评估改善患者生活质量的可行性。 结果 留置输尿管支架患者的主要症状为疼痛和血尿，而尿频、尿急、发热和性生活相关的症状少见。留置输尿管支架患者的症状评分在术后第3天最高，此后，除外附加问题患者其他维度的评分都有不同程度下降。接受干预的患者USSQ总分（57.5±10.1 vs. 51.6±8.9，t=2.981，P=0.004）和泌尿系统症状评分（30.8±5.3 vs. 26.7±5.6，t=3.478，P<0.001）较干预前明显下降，差异具有统计学意义。 结论 基于USSQ的患者报告结局和临床干预措施能够有效改善上尿路结石患者的生活质量，具有较高的可行性和临床应用价值。

Abstract

Objective To investigate the feasibility of improving quality of life through outcome self-reporting and clinical intervention based on the Ureteral Stent Symptom Questionnaire（USSQ） for patients with upper tract urolithiasis. Methods We enrolled 106 patients with upper urinary tract calculi from June 2023 to June 2024 who underwent ureteral stent placement at The First Affiliated Hospital of Chongqing Medical University. We applied the USSQ to monitor the patients’ outcomes through their self-reports，and used the data to inform clinical interventions. The feasibility of this USSQ-based approach for improving patients’ quality of life was evaluated. Results The main symptoms after ureteral stent placement were pain and hematuria，while frequency，urgency，fever，and sexual problems were less common. The USSQ score was highest on the third day after operation，and thereafter declined in all the dimensions. except the additional problem. After intervention，the total USSQ score （57.5±10.1 vs. 51.6±8.9，t=2.981，P=0.004） and urinary symptom score （30.8±5.3 vs. 26.7±5.6，t=3.478，P<0.001） were significantly decreased. USSQ-based outcome self-reporting and clinical intervention could reduce symptom scores and improve patients’ quality of life. Conclusion USSQ-based outcome monitoring and management are feasible and effective for improving the quality of life of patients with upper tract urolithiasis.

关键词

输尿管支架 / 输尿管支架症状评分问卷 / 患者自我报告 / 生活质量

Key words

ureteral stent / ureteral stent symptom questionnaire / patient self-report / quality of life