隔物灸法辅助治疗伴躯体症状抑郁症的临床疗效

Clinical efficacy of indirect moxibustion in the treatment of depression with somatic symptoms

摘要

目的 探究隔物灸法辅助治疗伴躯体症状抑郁症的临床疗效,评估其改善患者情绪障碍与躯体不适的作用,为抑郁症的中医干预提供依据。方法 选取2022年10月至2023年9月在山东省戴庄医院住院治疗的伴躯体症状抑郁症患者120例,按照随机数字表法分为对照组与观察组(每组n=60),对照组行舍曲林口服、心理干预等常规抗抑郁治疗,观察组在对照组治疗的基础上联合隔物灸法治疗,取穴神阙、关元、双侧神门、双侧足三里,每周治疗3次,治疗6周。比较两组疗效、汉密尔顿抑郁量表(HAMD-17)和汉密尔顿焦虑量表(HAMA)评分。结果 观察组总有效率93.33%(56/60),高于对照组的73.33%(44/60),差异有统计学意义(χ²=4.396,P=0.036);两组治疗前HAMD、HAMA评分比较差异不明显(P＞0.05),治疗后观察组HAMD、HAMA评分分别为(8.98±2.19)分、(6.93±1.82)分,低于对照组的(13.03±2.48)分、(10.12±2.19)分,差异有统计学意义(t=9.482,8.678,P＜0.05)。两组治疗前后HAMD、HAMA评分差值比较,观察组的(25.34±5.72)分、(19.32±3.15)分,高于对照组的(22.07±4.96)分、(16.45±3.02)分,差异具有统计学意义(t=3.346,5.094,P＜0.05)。结论 隔物灸法辅助治疗伴有躯体症状抑郁症患者,可有效改善患者的抑郁与焦虑情绪,促进躯体症状改善,疗效可靠。

Abstract

Objective To explore the clinical efficacy of indirect moxibustion in the treatment of depression with somatic symptoms,and to evaluate its effect on improving patients′ emotional disorders and somatic discomfort,providing evidence-based support for traditional Chinese medicine intervention in depression. Methods Clinical data of 120 patients with depression accompanied by somatic symptoms from Daizhuang Hospital in Shandong Province from October 2022 to September 2023 were collected.They were divided into a control group and an observation group (n=60 in each group) according to a random number table method.The control group received conventional antidepressant treatment, including oral administration of sertraline and psychological intervention.The observation group received combined indirect moxibustion treatment,on acupoints,including Shenque (CV 8),Guanyuan (CV 4),bilateral Shenmen (HT 7),and bilateral Zusanli (ST 36).The treatment was administered three times per week for 6 weeks.The efficacy of the two groups and the scores of the Hamilton Depression Scale (HAMD-17) and Hamilton Anxiety Scale (HAMA) were compared. Results The total effective rate in the observation group was 93.33%(56/60),which was higher than that in the control group 73.33%(44/60), the difference was statistically significant (χ²=4.396,P=0.036).There was no significant difference in the scores of HAMD and HAMA between the two groups before treatment (P＞0.05).After treatment, the scores of HAMD and HAMA in the observation group were 8.98±2.19 and 6.93±1.82,respectively,which were lower than those in the control group 13.03±2.48 and 10.12±2.19,respectively.The differences were statistically significant (t=9.482,8.678,P＜0.05).Furthermore,the differences in the scores before and after treatment in the observation group were 25.34±5.72 and 19.32±3.15,respectively,which were higher than those in the control group 22.07±4.96 and 16.45±3.02,respectively.The difference were statistically significant (t=3.346,5.094,P＜0.05). Conclusion Indirect moxibustion as an adjunctive therapy for patients with depression accompanied by somatic symptoms can effectively alleviate their depressive and anxious moods,improve somatic symptoms,and demonstrate reliable clinical efficacy.

关键词

抑郁症 / 躯体症状 / 隔物灸 / 中医外治法

Key words

Depression / Somatic symptoms / Indirect moxibustion / External therapy of traditional Chinese medicine

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基金资助

济宁市重点研发计划(2022YXNS196)