中药逆转药物耐药性的研究进展

Research Progress on Reversal of Drug Resistance by Traditional Chinese Medicine

摘要

药物耐药性已成为当前公共卫生领域的严峻挑战，耐药所致死亡人数逐年攀升，社会经济负担持续加重，亟需探寻有效防控策略。中医药底蕴深厚、临床经验丰富，在逆转抗感染、抗肿瘤药物耐药方面具备独特优势与应用潜力。对中药逆转抗感染及抗肿瘤药物耐药的作用机制及临床应用进行综述，总结中医药干预耐药的优势和局限性，旨在为中医药攻克耐药性难题提供理论依据与研究新思路。

Abstract

Drug resistance has become a severe challenge in the field of public health. The death toll caused by drug resistance increases year by year, and the socioeconomic burden continues to escalate. It is imperative to explore effective prevention and control strategies. With a profound theoretical foundation and extensive clinical experience, traditional Chinese medicine possesses unique advantages and application potential in reversing anti-infective and anti-tumor drug resistance. This paper reviews the mechanisms and clinical application of traditional Chinese medicine in reversing anti-infective and anti-tumor drug resistance, and summarizes its advantages and limitations, aiming to provide a theoretical basis and new research directions for tackling drug resistance via traditional Chinese medicine.

关键词

中药 / 抗生素耐药性 / 肿瘤耐药 / 天然产物

Key words

traditional Chinese medicine / antibiotic resistance / tumor drug resistance / natural products

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