六西格玛管理法对肿瘤化疗药物配置效率、配置质量及准确性影响的研究

Study on the Influence of Six Sigma Management Method on Pharmaceutical Dispensing Efficiency, Quality and Accuracy of Tumor Chemotherapy Drugs

摘要

目的 探讨六西格玛管理法对肿瘤化疗药物配置效率、配置质量及准确性的影响。方法 回顾性选取2024年6月至2025年5月在解放军联勤保障部队第903医院肿瘤科接受静脉化疗的100例患者，根据同期静脉用药调配中心（Pharmacy Intravenous Admixture Services，PIVAS）管理模式不同分为对照组和观察组，各50例。对照组在2024年6月至11月采用传统常规管理模式，观察组在2024年12月至2025年5月采用六西格玛管理法。比较2组患者的药物配置效率、配置质量及配置准确性。结果 与对照组相比，观察组审方核对时间、排药印签时间、药物冲配时间、打包核对时间及总配置时间均显著缩短（P< 0.05）；观察组审核制度、药品管理、安全管理得分均显著高于对照组，药物送达及时率显著升高（ P< 0.05）；观察组配置差错总发生率显著低于对照组（ P< 0.05）。结论 六西格玛管理法通过系统优化肿瘤化疗药物配置流程，显著提升配置效率，改善配置质量，降低配置差错总发生率，为临床肿瘤化疗患者提供更安全、高效的用药保障，值得在PIVAS推广应用。

Abstract

Objective To explore the influence of Six Sigma management method on pharmaceutical dispensing efficiency, quality and accuracy of tumor chemotherapy drugs. Methods A total of 100 patients who received intravenous chemotherapy in the Department of Oncology, The 903rd Hospital of the PLA Joint Logistic Support Force, from June 2024 to May 2025 were enrolled retrospectively. According to different management modes of Pharmacy Intravenous Admixture Services (PIVAS), the patients were divided into a control group and an observation group, with 50 cases in each group. The control group adopted the conventional management mode from June to November 2024, while the observation group adopted the Six Sigma management method from December 2024 to May 2025. The pharmaceutical dispensing efficiency, quality and accuracy were compared between the two groups. Results Compared with the control group, the prescription review and verification time, drug sorting and labeling time, drug compounding time, packaging verification time and total dispensing time were significantly shorter in the observation group (P< 0.05). The scores of auditing system, drug management and safety management in the observation group were significantly higher than those in the control group, and the on-time drug delivery rate was significantly increased ( P< 0.05). The total incidence of dispensing errors in the observation group was significantly lower than that in the control group ( P< 0.05). Conclusion Six Sigma management method can significantly improve dispensing efficiency, optimize dispensing quality and reduce the incidence of dispensing errors by systematically optimizing the dispensing process of tumor chemotherapy drugs. It can provide a safer and more efficient medication guarantee for patients undergoing tumor chemotherapy in clinical practice, and is worthy of popularization and application in PIVAS.

关键词

肿瘤化疗药物 / 六西格玛管理法 / 配置效率 / 配置质量 / 配置准确性

Key words

tumor chemotherapy drugs / Six Sigma management method / dispensing efficiency / dispensing quality / dispensing accuracy

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