多聚脱氧核糖核苷酸在临床治疗及医疗美容领域的应用现状

Current Applications of Polydeoxyribonucleotide in Clinical Treatment and Medical Aesthetics

摘要

多聚脱氧核糖核苷酸（polydeoxyribonucleotide，PDRN）是降解后的单链脱氧寡核苷酸构成的混合物，是近年来医疗美容和临床治疗的一大研究热点。通过对 PDRN 的基本理化性质、作用机制和应用进展进行综述，系统梳理其在多种临床适应证及医疗美容领域中的应用与发展现状，并对现有的安全性证据及潜在风险进行探讨，以期为 PDRN 的临床规范应用及其在医疗美容产品中的开发应用提供参考。

Abstract

Polydeoxyribonucleotide (PDRN) is a mixture of degraded single-stranded oligodeoxynucleotides and has emerged as a major research focus in medical aesthetics and clinical treatment in recent years. This review summarizes the basic physicochemical properties, its mechanisms of action, and advances in its application of PDRN. It further delineates the current status of its application and development across a range of clinical indications and in the field of medical aesthetics, and discusses the available safety evidence and potential risks. This review aims to provide a reference for the standardized clinical use of PDRN and its development for medical aesthetic applications.

关键词

多聚脱氧核糖核苷酸 / 临床治疗 / 医疗美容 / 安全性风险

Key words

polydeoxyribonucleotide / clinical treatment / medical aesthetics / safety risks

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