多肽类药物口服递送——基础、临床与产业转化研究进展

胡富强

药学进展 ›› 2026, Vol. 50 ›› Issue (4) : 289 -292.

PDF (3076KB)
药学进展 ›› 2026, Vol. 50 ›› Issue (4) : 289 -292. DOI: 10.20053/j.issn1001-5094.202605190464
评述

多肽类药物口服递送——基础、临床与产业转化研究进展

作者信息 +

Author information +
文章历史 +
PDF (3149K)

摘要

引用本文

引用格式 ▾
胡富强. 多肽类药物口服递送——基础、临床与产业转化研究进展[J]. 药学进展, 2026, 50(4): 289-292 DOI:10.20053/j.issn1001-5094.202605190464

登录浏览全文

4963

注册一个新账户 忘记密码

参考文献

[1]

Peri R V, Anchan H, Jonnalagadda K,et al. Designing GLP—1 delivery: structural perspectives and formulation approaches for optimized therapy[J].Nutr Diabetes, 2025, 15(1): 53.

[2]

Mehrotra S, Kalyan Bg P, Nayak P G,et al. Recent progress in the oral delivery of therapeutic peptides and proteins: overview of pharmaceutical strategies to overcome absorption hurdles[J].Adv Pharm Bull, 2024, 14(1): 11-33.

[3]

Kjeldsen T B, Hubálek F, Tagmose T M,et al. Engineering of orally available, ultralong—acting insulin analogues: discovery of OI338 and OI320[J].J Med Chem, 2021, 64(1): 616-628.

[4]

Petersen S B, Nielsen L G, Rahbek U L,et al. Colonic absorption of salmon calcitonin using tetradecyl maltoside (TDM) as a permeation enhancer[J].Eur J Pharm Sci, 2013, 48(4/5): 726-734.

[5]

Weng H, Hu L, Hu L,et al. The complexation of insulin with sodium N—[8—(2—hydroxybenzoyl)amino]—caprylate for enhanced oral delivery: effects of concentration, ratio, and pH[J].Chin Chem Lett, 2022, 33(4): 1889-1894.

[6]

Twarog C, Fattah S, Heade J,et al. Intestinal permeation enhancers for oral delivery of macromolecules: a comparison between salcaprozate sodium (SNAC) and sodium caprate (C10)[J].Pharmaceutics, 2019, 11(2): 78.

[7]

Griesser J, Hetényi G, Moser M,et al. Hydrophobic ion pairing: key to highly payloaded self—emulsifying peptide drug delivery systems[J].Int J Pharm, 2017, 520(1/2): 267-274.

[8]

Muntoni E, Anfossi L, Milla P,et al.Glargine insulin loaded lipid nanoparticles: oral delivery of liquid and solid oral dosage forms[J].Nutr Metab Cardiovasc Dis, 2021, 31(2): 691-698.

AI Summary AI Mindmap
PDF (3076KB)

78

访问

0

被引

详细

导航
相关文章

AI思维导图

/

〈 〉