数字减影血管造影下经鼻肠梗阻导管置入联合序贯肠内营养治疗对粘连性小肠梗阻患者的影响
薛英玲 , 彭星华 , 曹玉庆
中国现代医学杂志 ›› 2026, Vol. 36 ›› Issue (08) : 25 -30.
数字减影血管造影下经鼻肠梗阻导管置入联合序贯肠内营养治疗对粘连性小肠梗阻患者的影响
Effect of DSA-guided transnasal intestinal obstruction catheterization combined with sequential enteral nutrition on patients with adhesive small bowel obstruction
目的 探讨数字减影血管造影(DSA)下经鼻肠梗阻导管置入联合序贯肠内营养(EN)治疗对粘连性小肠梗阻患者的影响。 方法 选取2024年2月—2025年8月邯郸市第一医院收治的98例粘连性小肠梗阻患者,随机分为对照组与观察组,各49例。对照组实施常规保守治疗与常规营养支持,观察组实施DSA下经鼻肠梗阻导管置入联合序贯EN治疗。比较两组临床疗效、症状与体征改善情况[腹胀腹痛缓解时间、恢复EN时间、恢复排气时间、恢复排便时间、24 h引流量、住院时间]、营养指标[血清白蛋白(Alb)、前白蛋白(PA)、血红蛋白(Hb)]、炎症因子[C反应蛋白(CRP)、白细胞介素-6(IL-6)、白细胞计数(WBC)]、并发症发生情况。 结果 观察组总有效率高于对照组(P <0.05)。观察组腹胀腹痛缓解时间、恢复EN时间、恢复排气时间、恢复排便时间及住院时间均短于对照组(P <0.05),24 h引流量少于对照组(P <0.05)。对照组与观察组治疗前Alb、PA、Hb比较,差异均无统计学意义(P >0.05)。观察组治疗后Alb、PA均高于对照组(P <0.05)。观察组治疗前后Alb、PA的差值均大于对照组(P <0.05)。对照组与观察组治疗前CRP、IL-6、WBC比较,差异均无统计学意义(P >0.05)。观察组治疗后CRP、IL-6、WBC均低于对照组(P <0.05)。观察组治疗前后CRP、IL-6、WBC的差值均大于对照组(P <0.05)。观察组并发症总发生率低于对照组(P <0.05)。 结论 DSA下经鼻肠梗阻导管置入联合序贯EN可有效缓解粘连性小肠梗阻症状,促进肠功能恢复,改善营养与炎症状态,减少并发症,具有较高的临床应用价值。
Objective To investigate the effect of digital subtraction angiography (DSA)-guided transnasal intestinal obstruction catheterization combined with sequential enteral nutrition (EN) on patients with adhesive small bowel obstruction. Methods A total of 98 patients with adhesive small bowel obstruction admitted to our hospital from February 2024 to August 2025 were enrolled and randomly divided into a control group and an observation group, with 49 cases in each group. The control group received conventional conservative treatment and routine nutritional support, while the observation group received DSA-guided transnasal intestinal obstruction catheterization combined with sequential EN. Clinical efficacy, improvement of symptoms and signs [time to relief of abdominal distension and pain, time to recovery of EN, time to first flatus, time to first defecation, 24-hour drainage volume, and length of hospital stay], nutritional indicators [serum albumin (Alb), prealbumin (PA), hemoglobin (Hb) ], inflammatory factors [C-reactive protein (CRP), interleukin-6 (IL-6), white blood cell count (WBC) ], and the incidence of complications were compared between the two groups. Results The overall effective rate of the observation group was higher than that of the control group (P < 0.05). The time to relief of abdominal distension and pain, time to recovery of EN, time to recovery of flatus, time to recovery of defecation, and length of hospital stay in the observation group were shorter than those in the control group (P < 0.05), and the 24-hour drainage volume was less in the observation group than that in the control group (P < 0.05). There were no statistically significant differences in Alb, PA, and Hb levels between the control group and the observation group before treatment, as determined by t-test (P > 0.05). After treatment, Alb and PA levels in the observation group were higher than those in the control group (P < 0.05). The differences in Alb and PA levels before and after treatment in the observation group were greater than those in the control group (P < 0.05). There were no statistically significant differences in CRP, IL-6, and WBC levels between the control group and the observation group before treatment, as determined by t-test (P > 0.05). After treatment, CRP, IL-6, and WBC levels in the observation group were lower than those in the control group (P < 0.05). The differences in CRP, IL-6, and WBC levels before and after treatment in the observation group were greater than those in the control group (P < 0.05). The overall incidence of complications in the observation group was lower than that in the control group (P < 0.05). Conclusion DSA-guided transnasal intestinal obstruction catheterization combined with sequential EN can effectively relieve symptoms of adhesive small bowel obstruction, promote recovery of intestinal function, improve nutritional and inflammatory status, and reduce complications, showing high clinical application value.
| [1] |
杨帆, 卢华, 郭丽. 宣肺通腑方联合针灸治疗粘连性肠梗阻的临床研究[J]. 中医药学报, 2025, 53(4): 82-86. |
| [2] |
BUNINO F M, LANZA E, SELLARO G, et al. Radiomic analysis based on abdominal CT-scan to predict strangulation in adhesive small bowel obstruction: preliminary results[J]. J Clin Med, 2025, 14(17): 6286. |
| [3] |
WANG S Q, ZHANG D W, LU H, et al. Conversion to open surgery in laparoscopic approach of adhesive small bowel obstruction: Predictive factors and its impact on short-term outcomes[J]. Am J Surg, 2025, 244: 116291. |
| [4] |
SUN Y H, HU Y L, SUN Y F. Development of a predictive model for the need for early surgery in patients with adhesive small-bowel obstruction[J]. J Int Med Res, 2024, 52(12): 3000605241308386. |
| [5] |
WANG H, ZHANG J R, TU P S, et al. Comparison of the effect between traditional conservation and nasointestinal tube placement in adhesive small bowel obstruction: a matched case-control study[J]. Asian J Surg, 2024, 47(5): 2168-2177. |
| [6] |
高峰, 杜彦斌, 寇天阔, 广泛粘连性小肠梗阻术中经鼻置入肠梗阻导管的临床疗效评价[J]. 国际外科学杂志, 2024, 51(1): 27-31. |
| [7] |
廖甜, 王永恒, 李澜, 数字减影血管造影引导下经侧孔快速交换法与传统鼻胃管减压治疗粘连性肠梗阻的疗效观察[J]. 临床外科杂志, 2024, 32(3): 289-292. |
| [8] |
高威, 余晨, 左伟, 经脐单部位腹腔镜手术联合术后早期EN在先天性十二指肠梗阻快速康复中的应用效果[J]. 天津医药, 2023, 51(5): 530-534. |
| [9] |
中华医学会肠外EN学分会, 中国国际医疗保健促进交流会外科康复促进学分会. 小肠梗阻的诊断与治疗中国专家共识(2023版)[J]. 中华胃肠外科杂志, 2023, 26(5): 401-409. |
| [10] |
魏宝中, 朱红侠. 腹腔镜肠粘连松解术对粘连性肠梗阻患者胃肠功能及血清PCT、PA水平的影响[J]. 北华大学学报(自然科学版), 2023, 24(3): 351-355. |
| [11] |
M L, G B, F F, et al. Enhanced recovery programs following adhesive small bowel obstruction surgery are feasible and reduce the rate of postoperative ileus: a preliminary study[J]. Langenbecks Arch Surg, 2024, 409(1): 191. |
| [12] |
CHOY K T, LE K D R, KONG J C H. Seprafilm® and adhesive small bowel obstruction in colorectal/abdominal surgery: an updated systematic review[J]. BMC Surg, 2024, 24(1): 291. |
| [13] |
HUANG Y Q, FU R M, LIU D D, et al. Keys to successful laparoscopic adhesiolysis for adhesive small bowel obstruction: a scoping review[J]. Heliyon, 2024, 10(14): e34359. |
| [14] |
柏丹, 席斌, 李权林, CT量化评估粘连性小肠梗阻患者腹腔镜操作空间的探讨[J]. 腹腔镜外科杂志, 2024, 29(11): 834-837. |
| [15] |
王蒙, 袁笑, 徐阿曼, 粘连性小肠梗阻术后复发危险因素及列线图模型构建[J]. 中国现代手术学杂志, 2023, 27(4): 282-287. |
| [16] |
王胜强, 张大玮, 刘海瑞, 腹腔镜手术与开放手术治疗粘连性小肠梗阻的对比分析[J]. 腹腔镜外科杂志, 2025, 30(7): 500-504. |
| [17] |
肖喜风, 夏琴琴, 丁斌. 红藤汤加减灌肠治疗粘连性肠梗阻的临床疗效研究[J]. 检验医学与临床, 2024, 21(8): 1049-1053. |
| [18] |
CHEN S Y, HUANG R, ZHANG Y, et al. A retrospective single-center study of transnasal ileus tube insertion accompanied with cap-assisted endoscopic advancement for malignant adhesive bowel obstruction[J]. Sci Rep, 2024, 14(1): 29227. |
| [19] |
张波, 陈帝, 康奎, 奥曲肽联合经鼻肠梗阻导管置入术对晚期恶性小肠梗阻的应用效果分析[J]. 肿瘤综合治疗电子杂志, 2023, 9(2): 166-169. |
| [20] |
黄湘俊, 刘建红, 黄浩强, DSA引导下经鼻型肠梗阻导管置入术治疗复杂性肠梗阻适宜技术的临床疗效[J]. 中国现代手术学杂志, 2023, 27(6): 439-443. |
| [21] |
黄娟芳, 谢长远, 吴丽华, 品管圈护理模式用于经鼻肠梗阻导管置入治疗粘连性肠梗阻的临床观察[J]. 中国基层医药, 2022, 29(5): 785-788. |
| [22] |
周森, 王文航, 刘少博. DSA引导下改良与常规肠梗阻导管置入术的疗效对比[J]. 河南医学研究, 2025, 34(2): 309-313. |
| [23] |
金瑶瑶, 张益明, 郑万琼. 理气通腑活血汤联合西医常规治疗粘连性肠梗阻40例[J]. 中国中医药科技, 2023, 30(2): 369-371. |
| [24] |
何杨, 侯志冰, 王烈, 床旁盲插经鼻型肠梗阻导管联合序贯EN治疗粘连性小肠梗阻的疗效[J]. 实用医学杂志, 2025, 41(8): 1175-1180. |
| [25] |
黄湘俊, 冯阳, 张昕旸. DSA引导下经鼻肠梗阻导管置入术治疗术后早期炎性肠梗阻的疗效[J]. 中国医师杂志, 2025, 27(4): 578-581. |
河北省卫生健康委员会医学科学研究课题计划项目(20251304)
/
| 〈 |
|
〉 |