不同运动方式介导下的白色脂肪组织棕色化

White Adipose Tissue Browning Mediated by Different Modes of Exercise

摘要

脂肪组织是一种具有多种生理功能的高度复杂的异质性组织, 不同部位、不同类型的脂肪组织在代谢特征上存在差异, 过多的白色脂肪组织(white adipose tissue, WAT)会造成肥胖, 而棕色脂肪组织(brown adipose tissue, BAT)在影响能量消耗方面起着重要作用, 近年来不断有研究证实运动能促进WAT棕色化, 这将对代谢健康大有裨益。WAT棕色化受运动方式、运动强度、运动时间等因素的影响, 该文总结了有氧运动、抗阻运动、高强度间歇训练、全身振动训练等对WAT棕色化的影响, 以便采取更佳的运动策略提高WAT棕色化, 进而改善肥胖和促进代谢健康。

Abstract

Adipose tissue is a highly complex and heterogeneous tissue with many physiological roles. Dif-ferent parts and types of adipose tissue have different metabolic characteristics. Excessive white adipose tis-sue (WAT) causes obesity, whereas brown adipose tissue (BAT) plays an important role in energy expenditure. In recent years, studies have confirmed that exercise can promote the browning of WAT, which is beneficial for metabolic health. WAT browning is affected by the exercise mode, exercise intensity and time, and other factors. Herein, the effects of aerobic exercise, resistance exercise, high-intensity interval training and whole-body vibration training on browning of WAT are summarized, with the aim of exploring more efficient exer-cise strategies to promote the browning of WAT, thereby preventing obesity and improving metabolic health.

关键词

白色脂肪组织棕色化 / 运动方式 / 解偶联蛋白1 / 肥胖 / 运动因子

Key words

browning of white adipose tissue / exercise mode / uncoupling protein 1 (UCP1) / obesity / exerkine