孤独症谱系障碍儿童的动态发育轨迹与基于神经可塑性和环境敏感期的精准干预

Dynamic developmental trajectories and precision intervention based on neuroplasticity and environmental sensitivity periods in children with autism spectrum disorder

摘要

孤独症谱系障碍(ASD)是一种复杂的神经发育障碍,主要表现为社会交往困难、沟通障碍及重复行为等特征。研究显示,ASD儿童的发育轨迹是动态的,受多种因素影响。对ASD机制的深入了解使神经可塑性(NP)和环境敏感期(ES)在干预效果中的重要性逐渐显现,尤其是干预时间窗的选择可能显著影响成效。因此,精准干预(PI)成为优化ASD儿童治疗的关键。本文探讨ASD儿童的发育轨迹,神经可塑性与环境敏感期的关系,以及如何制定更有效的干预策略,为ASD儿童的支持与治疗提供科学依据。

Abstract

Autism spectrum disorder (ASD) is a complex neurodevelopmental condition characterized by impairments in social communication, interaction, and restricted, repetitive behaviors.Research indicates that the developmental trajectories of ASD children are dynamic and influenced by multiple factors.A deeper understanding of ASD mechanisms has highlighted the critical role of neuroplasticity (NP) and environmental sensitivity periods (ES) in intervention efficacy, particularly as the timing of interventions may significantly impact outcomes.Consequently, precision intervention (PI) has emerged as a key strategy for optimizing treatment in ASD children.This article explores the developmental trajectories of ASD children, the relationship between neuroplasticity and environmental sensitivity periods, and how to formulate more effective intervention strategies, thereby providing a scientific foundation for supporting and treating children with ASD.

关键词

孤独症谱系障碍 / 动态发育轨迹 / 神经可塑性 / 环境敏感期 / 精准干预

Key words

autism spectrum disorder / dynamic developmental trajectory / neuroplasticity / environmental sensitivity period / precision intervention

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