妊娠糖尿病子代脑发育的神经影像学研究进展

Advances in neuroimaging research on brain development in offspring of gestational diabetic mothers

摘要

大量行为和认知评估结果表明,糖尿病母亲的子代(ODMs)面临较高的神经发育障碍风险。然而,针对ODMs大脑结构和功能的研究非常有限。该文系统回顾了超声检查、磁共振成像、脑磁图以及脑电图等神经影像学技术在ODMs中的应用,总结ODMs大脑结构与功能改变,旨在探索识别ODMs脑发育异常的早期线索,为儿童保健中早期识别及干预ODMs神经发育障碍儿童提供理论支持。

Abstract

Extensive behavioral and cognitive assessments have indicated that offspring of diabetic mothers (ODMs) are at a higher risk for neurodevelopmental disorders. However, studies on brain structure and function in ODMs remain very limited. This article reviews the application of neuroimaging techniques, including ultrasonography, magnetic resonance imaging, magnetoencephalography, and electroencephalography, to summarize alterations in brain structure and function in ODMs, with the aim of identifying early indicators of abnormal brain development and providing theoretical support for early child healthcare interventions.

关键词

妊娠期糖尿病 / 神经影像学 / 大脑结构与功能 / 子代

Key words

gestational diabetes mellitus / neuroimaging / brain structure and function / offspring

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