《Eur Urol Focus》:尿液肿瘤DNA液体活检有望革新膀胱癌管理模式

徐珊

现代泌尿外科杂志 ›› 2026, Vol. 31 ›› Issue (4) : 394 -394.

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现代泌尿外科杂志 ›› 2026, Vol. 31 ›› Issue (4) : 394 -394. DOI: 10.12483/j.issn.1009-8291.2026.04.017
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《Eur Urol Focus》:尿液肿瘤DNA液体活检有望革新膀胱癌管理模式

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膀胱癌 / 尿液肿瘤DNA / 液体活检 / 早期诊断 / 微小残留病灶 / 复发监测

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徐珊. 《Eur Urol Focus》:尿液肿瘤DNA液体活检有望革新膀胱癌管理模式[J]. 现代泌尿外科杂志, 2026, 31(4): 394-394 DOI:10.12483/j.issn.1009-8291.2026.04.017

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参考文献

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LEE J, CHEN F, LOPEZ-BELTRAN A, et al. Urinary tumor DNA-based liquid biopsy in bladder cancer management: a systematic review[J]. Eur Urol Focus, 2025, 11(6): 978-990.

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DUDLEY JC, SCHROERS-MARTIN J, LAZZARESCHI DV, et al. Detection and surveillance of bladder cancer using urine tumor DNA[J]. Cancer Discov, 2019, 9(4): 500-509.

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STRANDGAARD T, LINDSKROG SV, NORDENTOFT I, et al. Elevated T-cell exhaustion and urinary tumor DNA levels are associated with bacillus calmette-guérin failure in patients with non-muscle-invasive bladder cancer[J]. Eur Urol, 2022, 82(6): 646-656.

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RAC G, PATEL HD, JAMES C, et al. Urinary comprehensive genomic profiling predicts urothelial carcinoma recurrence and identifies responders to intravesical therapy[J]. Mol Oncol, 2024, 18(2): 291-304.

[5]

ZHANG R, ZANG J, JIN D, et al. Urinary tumor DNA MRD Analysis to Identify responders to neoadjuvant immunotherapy in muscle-invasive bladder cancer[J]. Clin Cancer Res, 2023, 29(20): 4040-4046.

[6]

CHAUHAN PS, CHEN K, BABBRA RK, et al. Urine tumor DNA detection of minimal residual disease in muscle-invasive bladder cancer treated with curative-intent radical cystectomy: a cohort study[J]. PLoS Med, 2021, 18(8): e1003732.

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