普外科研究的桥梁：实验动物模型的研究与应用

摘要

2014—2025年，普外科动物模型研究取得重要进展。采用文献计量学方法，分析该领域研究热点并综述主要手术在动物模型上的应用。研究发现，过去十余年中，普外科动物模型的研究逐年增加，主要集中在微创手术、消化系统疾病手术、癌症研究等领域。热点词频分析显示，手术技术（如微创手术和腹腔镜手术）、疾病模型（如纤维化、糖尿病、乳腺癌和急性肾损伤）、麻醉和药物（如全身麻醉、丙泊酚和麻醉诱导的神经毒性）及外科教育和培训（如手术模拟和技能训练）等领域。这些研究热点反映了普外科在手术方法优化、疾病机制探究、麻醉安全性及外科医师培训等方面的关注和发展方向。通过对普外科主要手术动物模型的研究汇总，探讨其在临床应用中的潜力和面临的挑战，并提出了未来研究的建议，以期推动普外科动物模型研究与应用的进一步发展。

关键词

普外科 / 手术训练 / 动物模型 / 动物麻醉

参考文献

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基金资助

山东省自然科学基金(ZR2022QH394)

山东省泰山学者-青年专家项目(tsqn202312242)