B/C 基因型的乙型肝炎病毒在不同丙氨酸氨基转移酶状态下对 Th17、Treg 细胞及其比率的影响

高鹏 ,  刘燕玲 ,  李俊峰 ,  姚立琼

北京大学学报(医学版) ›› 2026, Vol. 58 ›› Issue (3) : 674 -677.

PDF (567KB)
北京大学学报(医学版) ›› 2026, Vol. 58 ›› Issue (3) : 674 -677. DOI: 10.19723/j.issn.1671-167X.2026.03.031
短篇论著

B/C 基因型的乙型肝炎病毒在不同丙氨酸氨基转移酶状态下对 Th17、Treg 细胞及其比率的影响

作者信息 +

Author information +
文章历史 +
PDF (579K)

关键词

乙肝 / 基因型 / 丙氨酸氨基转移酶 / Th17 细胞 / Treg 细胞

Key words

引用本文

引用格式 ▾
高鹏,刘燕玲,李俊峰,姚立琼. B/C 基因型的乙型肝炎病毒在不同丙氨酸氨基转移酶状态下对 Th17、Treg 细胞及其比率的影响[J]. 北京大学学报(医学版), 2026, 58(3): 674-677 DOI:10.19723/j.issn.1671-167X.2026.03.031

登录浏览全文

4963

注册一个新账户 忘记密码

参考文献

[1]

Zamor PJ, Lane AM. Interpretation of HBV serologies[J]. Clin Liver Dis, 2021, 25 (4):689-709.

[2]

Pollicino T, Caminiti G. HBV-integration studies in the clinic: Role in the natural history of infection[J]. Viruses, 2021, 13 (3): 368.

[3]

Bello KE, Mat Jusoh TNA, Irekeola AA, et al. A recent preva- lence of hepatitis B virus(HBV)genotypes and subtypes in Asia: A systematic review and meta-analysis[J]. Healthcare, 2023, 11 (7):1011-1018.

[4]

Gu Y, Li X, Gu L, et al. An immuno-clinic score model for evaluating T cell immunity and predicting early antiviral therapy ef- fectiveness in chronic hepatitis B[J]. Aging, 2020, 12 (24):26063-26079.

[5]

Li K, Liu H, Guo T. Th17/Treg imbalance is an indicator of liver cirrhosis process and a risk factor for HCC occurrence in HBV pa- tients[J]. Clin Res Hepatol Gastroenterol, 2017, 41(4): 399 - 407.

[6]

Jose-Abrego A, Roman S, Laguna-Meraz S, et al. Host and HBV interactions and their potential impact on clinical outcomes[J]. Pathogens, 2023, 12(9):1146-1152.

[7]

Nicolini LA, Orsi A, Tatarelli P, et al. A global view to HBV chronic infection:Evolving strategies for diagnosis,treatment and prevention in immunocompetent individuals[J]. Int J Environ Res Public Health, 2019, 16(18): 3307.

[8]

Hogan S, Page A, Dixit S, et al. HBV prevalence in Sub-conti- nental countries:A systematic review and meta-analysis[J]. PLoS One, 2023, 18(12):e0295670.

[9]

Chen J, Li L, Yin Q, et al. A review of epidemiology and clinical relevance of hepatitis B virus genotypes and subgenotypes[J]. Clin Res Hepatol Gastroenterol, 2023, 47(7): 102180.

[10]

Wang L, Zeng X, Wang Z, et al. Recent advances in under- standing T cell activation and exhaustion during HBV infection[J]. Virol Sin, 2023, 38(6):851-859.

[11]

Wan Z, Zhou Z, Liu Y, et al. Regulatory T cells and T helper 17 cells in viral infection[J]. Scand J Immunol, 2020, 91 (5): e12873.

[12]

高鹏, 雒艳萍. 乙型肝炎病毒在不同丙氨酸氨基转移酶状态下对 Th17、Treg 细胞及其比率的影响[J]. 北京大学学报(医学版), 2022, 54(2):272-277.

[13]

Beňová K, Hancková M, Koći K, et al. T cells and their function in the immune response to viruses[J]. Acta Virol, 2020, 64(2): 131-143.

[14]

Cui D, Jiang D, Yan C, et al. Immune checkpoint molecules ex- pressed on CD4 +T cell subsets in chronic asymptomatic hepatitis B virus carriers with hepatitis B e antigen-negative[J]. Front Microbiol, 2022, 13: 887408.

[15]

Xu J, Zhan Q, Fan Y, et al. Human genetic susceptibility to hepatitis B virus infection[J]. Infect Genet Evol, 2021, 87: 104663.

[16]

Revill PA, Tu T, Netter HJ, et al. The evolution and clinical im- pact of hepatitis B virus genome diversity[J]. Nat Rev Gastroen- terol Hepatol, 2020, 17(10):618-634.

[17]

Fernandes da Silva C, Keeshan A, Cooper C. Hepatitis B virus genotypes influence clinical outcomes:A review[J]. Can Liver J, 2023, 6(3):347-352.

[18]

Likhitsup A, Lok AS. Understanding the natural history of hepati- tis B virus infection and the new definitions of cure and the end- points of clinical trials[J]. Clin Liver Dis, 2019, 23(3): 401 - 416.

基金资助

国家自然科学基金(81800528)

AI Summary AI Mindmap
PDF (567KB)

0

访问

0

被引

详细

导航
相关文章

AI思维导图

/

〈 〉