To address the issue that the detection, location, and isolation of irrelevant system components may fail in actual engineering applications, this paper explores the impact of coverage failure and uncovered failure on the system under conditions of successful and unsuccessful isolation of the irrelevant components, clarifies the logical relationship between them, and proposes the Imperfect Irrelevance Coverage Model (IICM). In the IICM, an isolation factor is proposed to quantify a probability of successful isolation related to the irrelevant component. The IICM can be compatible with the imperfect fault coverage model (IFCM) and the irrelevance coverage model (ICM). Also, a combinatorial method is proposed for the fault-tolerant system reliability quantitative analysis based on the binary decision diagram considering imperfect irrelevance coverage. The results of the case study show that: 1) IICM is universal and its combinatorial quantitative analysis method is effective; 2) Compared with the IFCM, the IICM can improve system reliability without increasing redundancy. Also, the IICM improves the ICM by considering the isolation impact of irrelevant components.
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