中医烙法治疗对改善扁桃体肥大患者睡眠质量及日间嗜睡程度的疗效观察

Observation on the therapeutic effect of TCM cauterization therapy on improving sleep quality and daytime sleepiness in patients with enlarged tonsils

摘要

目的 评估中医烙法治疗在改善Ⅱ度及Ⅲ度扁桃体肥大患者的睡眠质量和日间嗜睡程度方面的有效性，为中医烙法治疗在因扁桃体显著肥大而导致的睡眠障碍相关疾病中的临床应用提供科学依据。方法 采用前瞻性自身前后对照的设计方法。研究对象为扁桃体Ⅱ度及Ⅲ度肥大的患者128例，所有入组患者均接受中医烙法治疗。治疗前及治疗结束后1个月，对所有患者进行问卷调查，主要评估工具包括:Epworth嗜睡量表(epworth sleepiness scale，ESS)及匹兹堡睡眠测评量表(pittsburgh sleep quality index，PSQI)。数据以R软件(version 4.4.2)处理。结果 128例患者接受中医烙法治疗，平均治疗8.7次，所有患者均完成治疗前后的完整评估。数据显示，PSQI总分由治疗前的(19.40±1.19)分下降至治疗后的(5.90±1.61)分，差异有统计学意义(P<0.001)。在PSQI的七个维度上，均观察到了统计学上的改善(P均<0.001)。Epworth嗜睡量表评分结果显示，患者的嗜睡评分从治疗前的(1.29±0.62)分降低至治疗后的(0.22±0.42)分(P<0.001)。结论 本研究结果证明，对于Ⅱ度及Ⅲ度扁桃体肥大的患者，中医烙法治疗能改善患者的整体睡眠质量，有效缓解日间嗜睡状态。中医烙法治疗作为一种微创、安全且能保留扁桃体免疫功能的中医特色疗法，在治疗因扁桃体过度肥大而导致的睡眠障碍相关疾病中，具有重要的临床应用价值和推广前景，可作为扁桃体切除术之外的重要选择。

Abstract

Objective To evaluate the effectiveness of TCM cauterization therapy in improving the sleep quality and daytime sleepiness of patients with grade II and Ⅲ tonsillar hypertrophy, and to provide a scientific basis for the clinical application of TCM cauterization therapy in diseases related to sleep disorders caused by significant tonsillar hypertrophy. Methods A prospective self-control design was adopted. A total of 128 patients with grade II and Ⅲ tonsillar hypertrophy were included. All patients received TCM cauterization therapy. Before treatment and 1 month after treatment, questionnaires were conducted for all patients, and the main assessment tools included: Epworth Sleepiness Scale (ESS) and Pittsburgh Sleep Quality Index (PSQI). Data were processed using R software (version 4.4.2). Results 128 patients received TCM cauterization therapy, with an average of 8.7 treatments. All patients completed the complete assessment before and after treatment. The data showed that the total score of the Pittsburgh Sleep Quality Index (PSQI) decreased significantly from (19.40±1.19) points before treatment to (5.90±1.61) points after treatment, with a statistically significant difference (P<0.001). In the seven dimensions of PSQI, statistically significant improvements were observed (all P<0.001). The Epworth Sleepiness Scale (ESS) score results showed that the sleepiness score of patients decreased significantly from (1.29±0.62) points before treatment to (0.22±0.42) points after treatment (P<0.001). Conclusion The results of this study prove that for patients with grade II and Ⅲ tonsillar hypertrophy, TCM cauterization therapy can significantly improve the overall sleep quality and effectively relieve daytime sleepiness. TCM cauterization therapy, as a minimally invasive, safe, and therapy that retains the immune function of the tonsils, has important clinical application value and promotion prospects in the treatment of sleep disorder-related diseases caused by excessive tonsillar hypertrophy, and can be an important alternative to tonsillectomy.

关键词

中医烙法治疗 / 扁桃体肥大 / 睡眠质量 / 日间嗜睡 / 疗效观察

Key words

TCM cauterization therapy / Tonsillar hypertrophy / Sleep quality / Daytime sleepiness / Efficacy observation

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基金资助

中山市卫生健康局医学科研项目(2022J014)