早产儿母亲产后抑郁患病率及影响因素的Meta分析

Prevalence and influencing factors of postpartum depression among mothers of preterm infants: a meta-analysis

摘要

目的 通过Meta分析的方法探讨早产儿母亲产后抑郁现状及影响因素。方法 系统检索PubMed、Cochrane Library、Web of Science、Embase、Medline、知网、维普、中国生物医学文献、万方数据库.检索关于早产儿母亲产后抑郁筛查或影响因素的横断面研究,检索时间从建库至2024年4月10日.由2名研究者独立进行文献筛选、资料提取及质量评价,使用Stata 14.0软件进行Meta分析。结果 共纳入29项研究,涉及4669例研究对象,26个影响因素.Meta分析结果显示:早产儿母亲产后抑郁患病率为34.9%.不良心理健康史OR=1.81(95%CI:1.34~2.28)、早产儿病情严重程度OR=3.33(95%CI:2.18~4.49)、产妇压力水平OR=1.15(95%CI:1.04~1.26)、产妇消极情绪OR=3.23(95%CI:1.90~4.57)、早产儿使用有创机械通气OR=1.62(95%CI:1.03~2.54)、担心早产儿的预后OR=2.48(95%CI:1.58~3.39)、担心早产儿智力的发育OR=5.43(95%CI:2.04~8.82)、缺乏家庭支持OR=2.35(95%CI:1.32~3.38)8项为早产儿母亲产后抑郁的影响因素(P<0.05)。结论 早产儿母亲产后抑郁患病率高,影响因素较多.临床医务人员应加强对早产儿母亲产后抑郁的筛查和干预,关注该类人群的心理健康,提供心理护理或心理咨询服务,提高产后生活质量.

Abstract

Objective To investigate current status and influencing factors of postpartum depression in mothers who had preterm infants by meta-analysis. Methods PubMed, Cochrane Library, Web of Science, Embase, Medline, Zhi.com, Wipo, China Biomedical Literature, and Wanfang databases were systematically searched. The search aimed to retrieve cross-sectional studies on screening or influencing factors of postpartum depression in mothers of preterm infants from beginning of the databases' construction to April 10, 2024. Literature screening, data extraction, and quality assessments were performed independently by two researchers, and meta-analysis was performed using Stata 14.0 software. Results There were 29 studies included, involving 4669 study subjects and 26 influencing factors. Meta-analysis results showed that prevalence of postpartum depression in mothers of preterm infants was 34.9%. Adverse mental health history (OR=1.81, 95%CI: 1.34-2.28), severity of preterm infant's condition (OR=3.33, 95%CI: 2.18-4.49), maternal stress level (OR=1.15, 95%CI: 1.04-1.26), negative maternal mood (OR=3.23, 95%CI: 1.90-4.57), use of invasive mechanical ventilation for preterm infant (OR=1.62, 95%CI: 1.03-2.54), worrying about prognosis of the preterm infant (OR=2.48, 95%CI: 1.58-3.39), worrying about development of preterm infant's intelligence (OR=5.43, 95%CI: 2.04-8.82) and lack of family support (OR=2.35, 95%CI: 1.32-3.38) were all influential factors for postpartum depression in mothers of preterm infants (all P<0.05). Conclusion The prevalence of postpartum depression in mothers of preterm infants is high, and there are many influencing factors. Clinical staff should strengthen screening and intervention of postpartum depression in mothers of preterm infants, pay attention to mental health of this group of population, provide psychological care or psychological counseling services, so as to improve quality of life in postpartum period of these mothers.

关键词

产后抑郁 / 患病率 / 影响因素 / 早产儿 / 母亲 / Meta分析

Key words

postpartum depression / prevalence / influencing factor / preterm infant / mother / meta-analysis

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基金资助

云南省教育厅科学研究基金项目(2024J0290)

云南中医药大学护理学院科创基金项目(YZHCKY2406)