虚拟现实技术: 老年认知功能障碍新辅助疗法 *

李媛媛 ,  张宇 ,  郭晓航 ,  党业兴 ,  周姝冶 ,  王智昊

国际老年医学杂志 ›› 2026, Vol. 47 ›› Issue (1) : 89 -94.

PDF (972KB)
国际老年医学杂志 ›› 2026, Vol. 47 ›› Issue (1) : 89 -94. DOI: 10.3969/j.issn.1674-7593.2026.01.015
综述

虚拟现实技术: 老年认知功能障碍新辅助疗法 *

作者信息 +

Virtual reality-assisted cognitive rehabilitation: a novel pathway for supporting elderly minds

Author information +
文章历史 +
PDF (994K)

摘要

认知功能障碍是指个体的认知能力出现明显下降, 可能在语言理解、记忆、感知、执行功能等方面受损。认知功能障碍类疾病的发病率高、综合征发展快、疾病负担大, 给全球卫生和社会系统带来了挑战。虚拟现实 (VR) 技术作为一种非侵入性非药物治疗的方法, 具有强大的沉浸式和交互性特征, 可根据患者自身状态制定个性化计划。VR 技术在认知功能障碍的识别、检测、干预上已有成效。本文对 VR 技术作为认知功能障碍新的辅助治疗方法作一综述, 分析其在康复训练、检测方面的应用, 并指出它的优势、不足和未来发展方向。

Abstract

Cognitive impairment denotes a substantial deterioration in an individual's cognitive faculties, potentially encompassing deficiencies in language comprehension, memory, perception, executive function, and more areas. Cognitive impairment disorders are marked by a high prevalence, swift symptom progression, and considerable illness burden, presenting significant challenges to global health and social systems. Virtual reality (VR) technology, as a non-invasive and non-pharmacological therapy method, facilitates the creation of individualized plans customized to the patient's condition through its immersive and interactive capabilities. Virtual reality has shown beneficial in the identification, evaluation, and intervention of cognitive impairment. This paper comprehensively discusses VR technology as an innovative adjunctive treatment for cognitive impairment, examines its applications in rehabilitation training and evaluation, and underscores its benefits, drawbacks, and prospective developments.

关键词

虚拟现实技术 / 老年人 / 认知功能障碍 / 认知康复

Key words

Virtual reality technology / Elderly / Cognitive impairment / Cognitive rehabilitation

引用本文

引用格式 ▾
李媛媛,张宇,郭晓航,党业兴,周姝冶,王智昊. 虚拟现实技术: 老年认知功能障碍新辅助疗法 *[J]. 国际老年医学杂志, 2026, 47(1): 89-94 DOI:10.3969/j.issn.1674-7593.2026.01.015

登录浏览全文

4963

注册一个新账户 忘记密码

参考文献

[1]

Ito K, Chapman R, Pearson S D, et al. Evaluation of the cost—effectiveness of drug treatment for Alzheimer disease in a simulation model that includes caregiver and societal factors[J]. JAMA Netw Open, 2021, 4(10): e2129392.

[2]

Chen Y X, Liang N, Li X L, et al. Diagnosis and treatment for mild cognitive impairment: a systematic review of clinical practice guidelines and consensus statements[J]. Front Neurol, 2021, 12: 719849.

[3]

Coyle H, Traynor V, Solowij N . Computerized and virtual reality cognitive training for individuals at high risk of cognitive decline: systematic review of the literature[J]. Am J Geriatr Psychiatry, 2015, 23(4): 335-359.

[4]

Zhu K, Zhang Q, He B, et al. Immersive virtual reality—based cognitive intervention for the improvement of cognitive function, depression, and perceived stress in older adults with mild cognitive impairment and mild dementia: pilot pre—post study[J]. JMIR Serious Games, 2022, 10(1): e32117.

[5]

Rabinovici G D, La Joie R . Amyloid—targeting monoclonal antibodies for Alzheimer disease[J]. JAMA, 2023, 330(6): 507-509.

[6]

Yondjo J, Siette J . “VR is the future”: perspectives of healthcare professionals on virtual reality as a diagnostic tool for dementia status in primary care[J]. BMC Med Inform Decis Mak, 2024, 24(1): 9.

[7]

Liao Y Y, Chen I H, Lin Y J, et al. Effects of virtual reality—based physical and cognitive training on executive function and dual—task gait performance in older adults with mild cognitive impairment: a randomized control trial[J]. Front Aging Neurosci, 2019, 11: 162.

[8]

Siette J, Adam P J, Harris C B . Acceptability of virtual reality to screen for dementia in older adults[J]. BMC Geriatr, 2024, 24(1): 493.

[9]

Marín—Medina D S, Arenas—Vargas P A, Arias—Botero J C, et al. New approaches to recovery after stroke[J]. Neurol Sci, 2024, 45(1): 55-63.

[10]

Kumar A, Pareek V, Faiq M A, et al. Adult neurogenesis in humans: a review of basic concepts, history, current research, and clinical implications[J]. Innov Clin Neurosci, 2019, 16(5/6): 30-37.

[11]

Mekbib D B, Zhao Z, Wang J, et al. Proactive motor functional recovery following immersive virtual reality—based limb mirroring therapy in patients with subacute stroke[J]. Neurotherapeutics, 2020, 17(4): 1919-1930.

[12]

Connors M H, Teixeira—Pinto A, Ames D, et al. Apathy and depression in mild cognitive impairment: distinct longitudinal trajectories and clinical outcomes[J]. Int Psychogeriatr, 2023, 35(11): 633-642.

[13]

Zygouris S, Giakoumis D, Votis K, et al. Can a virtual reality cognitive training application fulfill a dual role? Using the virtual supermarket cognitive training application as a screening tool for mild cognitive impairment[J]. J Alzheimers Dis, 2015, 44(4): 1333-1347.

[14]

Zhu S, Sui Y, Shen Y, et al. Effects of virtual reality intervention on cognition and motor function in older adults with mild cognitive impairment or dementia: a systematic review and meta—analysis[J]. Front Aging Neurosci, 2021, 13: 586999.

[15]

Buele J, Avilés—Castillo F, Del—Valle—Soto C, et al. Effects of a dual intervention (motor and virtual reality—based cognitive) on cognition in patients with mild cognitive impairment: a single—blind, randomized controlled trial[J]. J Neuroeng Rehabil, 2024, 21(1): 130.

[16]

Perra A, Riccardo C L, De Lorenzo V, et al. Fully immersive virtual reality—based cognitive remediation for adults with psychosocial disabilities: a systematic scoping review of methods intervention gaps and meta—analysis of published effectiveness studies[J]. Int J Environ Res Public Health, 2023, 20(2): 1527.

[17]

Kang J M, Kim N, Lee S Y, et al. Effect of cognitive training in fully immersive virtual reality on visuospatial function and frontal—occipital functional connectivity in predementia: randomized controlled trial[J]. J Med Internet Res, 2021, 23(5): e24526.

[18]

GBD 2016 Stroke Collaborators . Global, regional, and national burden of stroke, 1990—2016: a systematic analysis for the Global Burden of Disease Study 2016[J]. Lancet Neurol, 2019, 18(4): 439-458.

[19]

Quinn T J, Richard E, Teuschl Y, et al. European Stroke Organisation and European Academy of Neurology joint guidelines on post—stroke cognitive impairment[J]. Eur Stroke J, 2021, 6(3): Ⅰ-ⅩⅩⅩⅧ.

[20]

Stolwyk R J, Mihaljcic T, Wong D K, et al. Poststroke cognitive impairment negatively impacts activity and participation outcomes: a systematic review and meta—analysis[J]. Stroke, 2021, 52(2): 748-760.

[21]

Liu Y, Liu S, Tang C, et al. Transcranial alternating current stimulation combined with sound stimulation improves cognitive function in patients with Alzheimer's disease: study protocol for a randomized controlled trial[J]. Front Aging Neurosci, 2023, 14: 1068175.

[22]

Remsik A, Young B, Vermilyea R, et al. A review of the progression and future implications of brain—computer interface therapies for restoration of distal upper extremity motor function after stroke[J]. Expert Rev Med Devices, 2016, 13(5): 445-454.

[23]

Huang X, Naghdy F, Naghdy G, et al. Clinical effectiveness of combined virtual reality and robot assisted fine hand motion rehabilitation in subacute stroke patients[C]// 2017 International Conference on Rehabilitation Robotics (ICORR). July 17—20, 2017, London, UK. IEEE, 2017: 511-515.

[24]

Nguemeni C, Hiew S, Kögler S, et al. Split—belt training but not cerebellar anodal tDCS improves stability control and reduces risk of fall in patients with multiple sclerosis[J]. Brain Sci, 2021, 12(1): 63.

[25]

Elsner B, Kugler J, Pohl M, et al. Transcranial direct current stimulation (tDCS) for improving activities of daily living, and physical and cognitive functioning, in people after stroke[J]. Cochrane Database Syst Rev, 2020, 11(11): CD009645.

[26]

王莎, 郝利霞, 梁宇, . 经颅直流电刺激在不同类型老年脑卒中后认知障碍患者康复中的应用及相应参数的筛选[J]. 国际老年医学杂志, 2023, 44(6): 665-668.

[27]

Wang S , Hao L X , Liang Y , et al. Application of transcranial direct current stimulation in rehabilitation of elderly patients with cognitive impairment after stroke of different types and screening of corresponding parameters[J]. Int J Geriatr, 2023, 44(6): 665-668.

[28]

Huang Q, Jiang X, Jin Y, et al. Immersive virtual reality—based rehabilitation for subacute stroke: a randomized controlled trial[J]. J Neurol, 2024, 271(3): 1256-1266.

[29]

Cho D R, Lee S H . Effects of virtual reality immersive training with computerized cognitive training on cognitive function and activities of daily living performance in patients with acute stage stroke: a preliminary randomized controlled trial[J]. Medicine, 2019, 98(11): e14752.

[30]

Laver K E, Lange B, George S, et al. Virtual reality for stroke rehabilitation[J]. Cochrane Database Syst Rev, 2017, 11(11): CD008349.

[31]

Oliveira J, Gamito P, Lopes B, et al. Computerized cognitive training using virtual reality on everyday life activities for patients recovering from stroke[J]. Disabil Rehabil Assist Technol, 2022, 17(3): 298-303.

[32]

Chen X, Liu F, Lin S, et al. Effects of virtual reality rehabilitation training on cognitive function and activities of daily living of patients with poststroke cognitive impairment: a systematic review and meta—analysis[J]. Arch Phys Med Rehabil, 2022, 103(7): 1422-1435.

[33]

Alzheimer's Association . 2016 Alzheimer's disease facts and figures[J]. Alzheimers Dement, 2016, 12(4): 459-509.

[34]

Yi Y, Hu Y, Cui M, et al. Effect of virtual reality exercise on interventions for patients with Alzheimer's disease: a systematic review[J]. Front Psychiatry, 2022, 13: 1062162.

[35]

Bahar—Fuchs A, Martyr A, Goh A M, et al. Cognitive training for people with mild to moderate dementia[J]. Cochrane Database Syst Rev, 2019, 3(3): CD013069.

[36]

Johansen T, Matre M, Løvstad M, et al. Virtual reality as a method of cognitive training of processing speed, working memory, and sustained attention in persons with acquired brain injury: a protocol for a randomized controlled trial[J]. Trials, 2024, 25(1): 340.

[37]

Maggio M G, De Luca R, Molonia F, et al. Cognitive rehabilitation in patients with traumatic brain injury: a narrative review on the emerging use of virtual reality[J]. J Clin Neurosci, 2019, 61: 1-4.

[38]

Calabrò R S, Bonanno M, Torregrossa W, et al. Benefits of telerehabilitation for patients with severe acquired brain injury: promising results from a multicenter randomized controlled trial using nonimmersive virtual reality[J]. J Med Internet Res, 2023, 25: e45458.

[39]

Davis D H, Creavin S T, Yip J L, et al. Montreal cognitive assessment for the detection of dementia[J]. Cochrane Database Syst Rev, 2021, 7(7): CD010775.

[40]

Sabbagh M N, Boada M, Borson S, et al. Early detection of mild cognitive impairment (MCI) in primary care[J]. J Prev Alzheimers Dis, 2020, 7(3): 165-170.

[41]

Spooner D M, Pachana N A . Ecological validity in neuropsychological assessment: a case for greater consideration in research with neurologically intact populations[J]. Arch Clin Neuropsychol, 2006, 21(4): 327-337.

[42]

Parsons T D . Virtual reality for enhanced ecological validity and experimental control in the clinical, affective and social neurosciences[J]. Front Hum Neurosci, 2015, 9: 660.

[43]

Yan M, Yin H, Meng Q, et al. A virtual supermarket program for the screening of mild cognitive impairment in older adults: diagnostic accuracy study[J]. JMIR Serious Games, 2021, 9(4): e30919.

[44]

Xu Y, Zhang C, Pan B, et al. A portable and efficient dementia screening tool using eye tracking machine learning and virtual reality[J]. NPJ Digit Med, 2024, 7(1): 219.

[45]

Cornacchia E, Bonvino A, Scaramuzzi G F, et al. Digital screening for early identification of cognitive impairment: a narrative review[J]. Wiley Interdiscip Rev Cogn Sci, 2025, 16(4): e70009.

[46]

Butler P M, Yang J, Brown R, et al. Smartwatch— and smartphone—based remote assessment of brain health and detection of mild cognitive impairment[J]. Nat Med, 2025, 31(3): 829-839.

[47]

Aramaki A L, Sampaio R F, Reis A C S, et al. Virtual reality in the rehabilitation of patients with stroke: an integrative review[J]. Arq Neuropsiquiatr, 2019, 77(4): 268-278.

[48]

Doniger G M, Beeri M S, Bahar—Fuchs A, et al. Virtual reality—based cognitive—motor training for middle—aged adults at high Alzheimer's disease risk: a randomized controlled trial[J]. Alzheimers Dement, 2018, 4: 118-129.

[49]

Aminov A, Rogers J M, Middleton S, et al. What do randomized controlled trials say about virtual rehabilitation in stroke? A systematic literature review and meta—analysis of upper—limb and cognitive outcomes[J]. J Neuroeng Rehabil, 2018, 15(1): 29.

[50]

Liu Q, Wang Y, Tang Q, et al. Do you feel the same as I do? Differences in virtual reality technology experience and acceptance between elderly adults and college students[J]. Front Psychol, 2020, 11: 573673.

[51]

Martirosov S, Bureš M, Zítka T . Cyber sickness in low—immersive, semi—immersive, and fully immersive virtual reality[J]. Virtual Real, 2022, 26(1): 15-32.

[52]

Kim O, Pang Y, Kim J H . The effectiveness of virtual reality for people with mild cognitive impairment or dementia: a meta—analysis[J]. BMC Psychiatry, 2019, 19(1): 219.

[53]

Torrisi M, Maresca G, De Cola M C, et al. Using telerehabilitation to improve cognitive function in post—stroke survivors: is this the time for the continuity of care?[J]. Int J Rehabil Res, 2019, 42(4): 344-351.

基金资助

*吉林省发展和改革委员会创新能力建设资金项目(2024C009-5)

AI Summary AI Mindmap
PDF (972KB)

154

访问

0

被引

详细

导航
相关文章

AI思维导图

/