老年难治性胃食管反流病的病因及治疗进展^*

Etiology and therapeutic advances of refractory gastroesophageal reflux disease in the elderly

摘要

老年人胃食管反流病具有症状不典型、食管损伤较重、并发症多等特点,还常伴随其他多种慢性疾病,诊断和治疗复杂,病程迁延,多数进展为难治性胃食管反流病(rGERD)。其病因复杂,治疗上中西医都积累了丰富经验,形成了较为完善的理论体系,中西医结合更展现出个体化治疗、整体调节以及副作用小的优势。该文对老年rGERD的病因及中西医治疗的当前进展作一综述,旨在为防治老年rGERD,提高老年人生活质量提供参考。

Abstract

Gastroesophageal reflux disease in the elderly is marked by unique symptoms, significant esophageal damage, and other consequences. It is frequently associated with numerous other chronic conditions, characterized by intricate diagnosis and therapy, an extended illness trajectory, and in most instances, advances to refractory gastroesophageal reflux disease (rGERD). Numerous factors contribute to this, and both traditional Chinese and Western medicine have amassed much expertise in therapy, establishing a very thorough theoretical framework. The amalgamation of Chinese and Western medicine further illustrates the benefits of personalized treatment, comprehensive regulation, and reduced side effects. This review examines the etiologies of rGERD in the elderly and the advancements in its treatment through traditional Chinese and Western medicine, with the objective of offering a reference for the prevention and management of rGERD in this demographic and enhancing their quality of life.

关键词

老年人 / 难治性胃食管反流病 / 病因 / 治疗

Key words

Elderly / Refractory gastroesophageal reflux disease / Etiology / Treatment