The neuroprotective strategy for stroke therapy

The neuroprotective strategy for stroke therapy

摘要

The ischemic stroke causes severe damage to human health. Effective treatment of stroke is in an urgent demand. Neuroprotective strategy is one of the most promising ways for stroke therapy. In the past decades, investigators have known a lot about the mechanism of ischemic neuronal death and revealed many detrimental pathways. Numerous molecules were suggested as potential targets for stroke therapy and a great amount of compounds was developed to target these molecules and pathways. However, almost none of them have reached clinical application in stroke treatment. In this review, we will discuss the neuroprotective strategy and its possible translational studies in stroke therapy.

关键词

stroke therapy / neuroprotective strategy / excitotoxicity