Update of personalized medicine in blood disorders

Update of personalized medicine in blood disorders

摘要

As it is known, more and more genes' single nucleotide polymorphisms (SNPs) were associated with some diseases, the pharmacokinetics and the targets of drug effects. Detecting specific genotypes could be helpful to choose specific regimen in different individuals, which could result in a better treatment effects and reduced adverse events. In addition, the abnormal chromosomes and fusion genes were common in hematological malignances. To detecting these associated genes could contribute to the precise selection of specific targeted therapy and the better understanding of the prognosis.

关键词

personalized medicine / single nucleotide polymorphism / blood disorder