The research of prediabetes intervention

The research of prediabetes intervention

摘要

Prediabetes is the necessary stage of type 2 diabetes（T2DM）, and also an independent risk factor of macrovascular and microvascular diseases.Referred to the related literature at home and abroad, we analyzed several large scale studies of prediabetes intervention.This article summarized the achievements of prediabetes intervention in recent years with western and Chinese medicine.It also showed a detailed discussion on effective ingredients and mechanism of Traditional Chinese medicine in improving glucose metabolism.A large number of clinical trials and animal experiments have proved that lots of Chinese medicines and extracts showed positive effect in improving glucose metabolism.The effective components mainly include alkaloids, flavones and so on.The mechanisms are primarily through repairing beta cells, promoting insulin secretion, improving insulin resistance and so forth.