The development of clinical type and personalized therapy for asthma: from bench to bed

The development of clinical type and personalized therapy for asthma: from bench to bed

摘要

With deep understanding of pathogenesis in asthma, this disorder with vast heterogeneity should be redefined by clinical, pathologic and molecular biological characteristics.As the target therapy has succeeded in specific subgroup of asthmatics according to “endotype” theory, “one size fits all” approach is facing major challenges.It implies traditional non specific asthma treatment such as corticosteroid, theophylline will turn to target therapy dominated specific treatment such as anti IgE, anti IL-5 antibody et al.These new therapies will open a brand new field for asthma treatment.