AIP1 and inflammatory responses in the cardiovascular system

Jiqin Zhang; Huanjiao Jenny Zhou; Weidong Ji; Min Wang

doi:10.3868/j.issn.2095-154x.2015.01.016EN

转化医学研究 ›› 2014, Vol. 4 ›› Issue (4) : 139 -139. DOI: 10.3868/j.issn.2095-154x.2015.01.016EN

综述

AIP1 and inflammatory responses in the cardiovascular system

Jiqin Zhang,Huanjiao Jenny Zhou,Weidong Ji,Min Wang

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AIP1 and inflammatory responses in the cardiovascular system

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摘要

AIP1 is a novel member of the Ras GTPase activating protein family.Recent studies suggest that AIP1 can function as a tumor suppressor in tumor cells, and also acts as a anti inflammatory protein in the cardiovascular system.In this review, we summarize the roles and mechanisms of AIP1 in inflammatory signaling and inflammation induced angiogenesis and atherosclerosis.