活动情况与血管性认知障碍肾阳虚证患者认知功能的相关性研究

A Study on the correlation between physical activity and cognitive function in patients with vascular cognitive impairment with kidney-yang deficiency

摘要

目的 探索血管性认知障碍肾阳虚证患者的活动情况与肾阳虚证及认知功能的相关性。方法 纳入120例血管性认知障碍肾阳虚证患者，采集其活动情况信息，并采用MoCA评估受试者的整体认知功能。通过Spearman相关性分析探讨活动情况与肾阳虚证或认知功能的相关性。结果 每周工作中步行（r=-0.217，P=0.018）和外出步行时间（r=-0.201，P=0.033）与肾阳虚评分呈负相关关系，每周乘车外出（r=0.308，P=0.001）和中体力家务劳动时间（r=0.196，P=0.035）与MoCA评分呈正相关关系。结论 运动可能在改善肾阳虚证与保护认知功能方面有一定潜能。

Abstract

Objective To explore the correlation between physical activity and kidney-yang deficiency and cognitive function in patients with vascular cognitive impairment with kidney-yang deficiency. Methods 120 patients diagnosed with vascular cognitive impairment with kidney-yang deficiency were enrolled, physical activity information was collected, and the Montreal Cognitive Assessment Scale (MoCA) was used to assess cognitive function. Spearman correlation analysis was performed to investigate the correlation between physical activity and kidney-yang deficiency and cognitive function. Results Time spent walking at work (r=-0.217, P=0.018) and walking outside (r=-0.201, P=0.033) per week were negatively correlated with kidney-yang deficiency syndrome scores, and time spent out in the car (r=0.308, P=0.001) and moderate physical housework (r=0.196, P=0.035) per week were positively correlated with MoCA scores. Conclusion Physical activity may have the potential to improve kidney-yang deficiency and protect cognitive function. Within specific classifications, walking at work and walking outside may be more closely associated with improvement of kidney-yang deficiency, and going out by car and moderate physical housework may be more closely associated with protection of cognitive function.

关键词

血管性认知障碍 / 肾阳虚 / 体力活动 / 认知功能

Key words

vascular cognitive impairment / kidney-yang deficiency / physical activity / cognitive function

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基金资助

北京中医药大学东方医院高水平能力建设项目“卓远”工程(DFRCZY-2024GJRC014)

国家重点研发计划项目(2018YFC1704303)