早期介入水滤红外线A照射治疗膝骨关节炎的疗效

Efficacy of early intervention with water-filtered infrared A irradiation for knee osteoarthritis

摘要

目的 分析早期介入水滤红外线A照射治疗膝骨性关节炎（KOA）的疗效及安全性。方法 2023年1月至2024年6月无锡市惠山区中医医院骨科收治KOA患者294例。采用随机数字表法将其分为3组，均行基础治疗加药物治疗加功能训练。对照组实施常规红外线照射治疗；常规介入组于患者病情稳定或急性期后介入水滤红外线A照射治疗；早期介入组于患者确诊时介入水滤红外线A照射治疗。观察比较3组患者治疗方案的疗效及安全性。结果 早期介入组在治疗后西安大略和麦克马斯特大学骨关节炎指数评分均显著低于常规介入组和对照组（P<0.05），且早期介入组和常规介入组总有效率显著高于对照组（P<0.05）。早期介入组在治疗后白细胞介素-1β、白细胞介素-6水平均显著低于常规介入组和对照组（P<0.05）。早期介入组在治疗后视觉模拟评分法评分显著低于常规介入组和对照组（P<0.05）。常规介入组和早期介入组不良反应总发生率显著低于对照组（P<0.05）。结论 早期介入水滤红外线A照射治疗KOA可有效改善患者膝关节功能，减轻炎症反应及疼痛感，且安全性良好。

Abstract

Objective To analyze the efficacy and safety of early interventional treatment for knee osteoarthritis (KOA) by water-filtered infrared A irradiation. Methods A total of 294 KOA patients admitted to Department of Orthopedic, Huishan Hospital of Traditional Chinese Medicine in Wuxi from January 2023 to June 2024, were selected by random number table method. They were divided into three groups by random number table method. All of the patients received basic therapy, drug therapy, functional training. The control group received conventional infrared radiation therapy. The conventional intervention group was treated by water-filtered infrared A irradiation after the patient's condition was stable or acute. The early intervention group was treated by water-filtered infrared A irradiation when the patients was diagnosed. The efficacy and safety of the three groups were observed and compared. Results After treatment, the score of the Western Ontario and McMaster University osteoarthritis index in early intervention group was significantly lower than that in conventional intervention group and control group (P<0.05). The total effective rate in early intervention group and conventional intervention group was significantly higher than that in control group (P<0.05). After treatment, the levels of interleukin-1β and interleukin-6 in early intervention group were significantly lower than those in conventional intervention group and control group (P<0.05). After treatment, the visual analog score of early intervention group was significantly lower than that of conventional intervention group and control group (P<0.05). The total incidence of adverse reactions in routine intervention group and early intervention group was significantly lower than that in control group (P<0.05). Conclusion Early intervention with water-filtered infrared A irradiation for KOA can effectively improve knee joint function, reduce inflammation and pain, and has good safety.

关键词

骨关节炎 / 膝关节 / 水滤红外线A照射

Key words

Osteoarthritis / Knee joint / Water-filtered infrared-A

参考文献

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基金资助

江苏医药职业学院临床教学基地科研发展专项课题(20229127)