如何提高自体脂肪移植存活率? —不同脂肪处理技术的比较与选择

How to improve the survival rate of autologous fat grafting? —Comparison and selection of different fat processing techniques

摘要

自体脂肪移植是一种将患者自身抽吸的脂肪重新注射到其他部位, 以填补组织容量缺损的整形手术。然而, 术后脂肪保留率不稳定是该技术面临的主要挑战。脂肪移植过程包含脂肪抽吸、处理纯化、注射及辅助处理等步骤, 其中每一步骤均可能影响脂肪保留率。为提升保留率, 临床上对各步骤均在不断优化, 而脂肪抽吸物的处理步骤尤为关键。本综述聚焦于脂肪处理纯化技术, 比较不同处理方法对脂肪保留率的影响, 旨在为获得理想移植效果提供参考。

Abstract

Autologous fat grafting is a plastic surgery procedure that involves re-injecting fat aspirated from the patient's own body into other sites to address tissue volume deficits. However, the instability of postoperative fat retention rate remains the primary challenge faced by this technique. The entire process of fat grafting comprises multiple steps, including fat aspiration, processing and purification, injection, and adjuvant treatment, each of which can affect the fat retention rate. To improve the retention rate, clinical optimizations have been proposed for each step, among which the processing of fat aspirate is particularly critical. This review focuses on fat processing and purification technologies, compares the effects of different processing methods on the retention rate, and provides a basis for achieving ideal grafting outcomes.

关键词

自体脂肪移植 / 脂肪处理纯化技术 / 脂肪保留率 / 新型脂肪处理技术 / 脂肪干细胞 / 脂肪细胞活性 / 纳米脂肪 / 基质血管成分

Key words

autologous fat grafting / fat processing and purification technology / fat retention rate / novel fat processing technology / adipose-derived stem cells / adipocyte viability / nanofat / stromal vascular fraction

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基金资助

国家自然科学基金面上项目(82372530)