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摘要
基于翻转课堂理念,探索新的有机化学实验教学方法,并以“二苯甲醇的重结晶”为例进行实践。在实践中,引导学生自主设计实验方案,考察不同单一溶剂及混合溶剂体系,结合分析天平和高效液相色谱仪测定产品产量及纯度。实践结果表明,新的实验教学方式能够有效增强学生学习的主观能动性,提高实验设计能力、创新思维及科研素养,为有机化学实验教学提供了一种新的模式。
Abstract
Based on the flipped classroom concept, new experimental teaching method for organic chemistry experiments is explored with the recrystallization of diphenylmethanol as a practice case. Students were guided to independently design experimental procedures, study different single-solvent and mixed-solvent systems, and assess the yield and purity of the products using analytical balance and high-performance liquid chromatography instruments. The results indicate that the new teaching approach effectively enhances students' learning initiative, experimental design ability, innovative thinking, and scientific literacy, providing a new model for the teaching of organic chemistry experiments.
关键词
Key words
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秦铭泽,冷雪,陈建超,赵明明,马超.
新型翻转课堂在有机化学实验中的应用——以“二苯甲醇的重结晶”为例[J].
高等药学教育研究, 2026, 44(1): 45-48 DOI:
| [1] |
谭晓虹, 董晓华, 杨辉, 等. 药学专业有机化学实验教学的实践与思考[J]. 河北北方学院学报(自然科学版), 2017, 33(2): 54-56.
|
| [2] |
Lage M J, Platt G J, Treglia M. Inverting the classroom: A gateway to creating an inclusive learning environment[J]. The Journal of Economic Education, 2000, 31(1): 30-43.
|
| [3] |
邵将. 高校翻转课堂教学模式优化设计与实践反思[J]. 教育现代化, 2018, 5(50): 341-342.
|
| [4] |
邓明捷, 李平. 药学类本科生实验教学改革实践与探索[J]. 温州医科大学学报, 2019, 49(9): 700-703.
|
| [5] |
教育部, 财政部. 国家发展改革委印发《关于高等学校加快“双一流”建设的指导意见》的通知[OL]. 教育部官网, (2018-08-20) [2025-02-07]. http://www.moe.gov.cn/srcsite/A22/moe_843/201808/t20180823_345987.html.
|
| [6] |
张开翔, 徐霞, 可钰, 等. 以药物研发为中心的多维度整合药学综合教学实验设计[J]. 药学教育, 2021, 37(5): 72-75.
|