人工智能在中西医结合防治心血管疾病中的应用研究进展

高山泉 ,  薛亚军 ,  佘飞 ,  彭朝权

新医学 ›› 2026, Vol. 57 ›› Issue (7) : 695 -706.

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新医学 ›› 2026, Vol. 57 ›› Issue (7) : 695 -706. DOI: 10.12464/j.issn.0253-9802.2026-0677
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人工智能在中西医结合防治心血管疾病中的应用研究进展

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Advances in the application of artificial intelligence in the prevention and treatment of cardiovascular diseases with integrated traditional Chinese and Western medicine

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摘要

心血管疾病(CVD)是我国居民首位死亡原因,中西医结合在CVD防治中具有独特优势,但中医诊疗客观量化标准不足、中西医数据异构难融合等问题制约其规范化发展。人工智能(AI)凭借多模态数据融合、机器学习等技术,为突破上述瓶颈提供了重要技术支撑。文章系统梳理AI核心技术与中西医结合的内在适配基础,从CVD风险预警、诊断、治疗、预后管理及临床决策辅助5个维度介绍该领域的应用现状与研究进展,分析当前存在的数据标准化程度不足、算法可解释性较弱、临床转化滞后等挑战,提出以标准化数据库建设、可解释性AI研发、真实世界临床验证等为核心的发展方向,以期推动AI与中西医结合深度融合,构建具有中国特色的CVD智能诊疗体系,为该领域的研究与临床转化提供参考。

Abstract

Cardiovascular disease (CVD) is the leading cause of death in China. Integrated traditional Chinese and Western Medicine (ITCWM) has unique advantages in the prevention and treatment of CVD. However, the lack of objective quantitative standards of traditional Chinese Medicine (TCM) and the challenges in the integration of heterogeneous data of TCM and western medicine restrict its standardized development. Artificial Intelligence (AI) relies on multimodal fusion, machine learning and other technologies to provide a critical path to break the above bottlenecks. We systematically sort out the adaptation logic of AI core technology and ITCWM, review the application status and research progress in this field across five dimensions of CVD risk warning, diagnosis, treatment, prognostic management, and clinical decision support, and analyze the challenges such as insufficient data standardization, poor interpretation of algorithms, and lagging clinical translation. Therefore, we propose an implementation approach centered on standardized database construction, interpretable AI research and development, and real-world clinical verification. The aim of this study is to promote the deep integration of AI with the ITCWM, build an intelligent diagnosis and treatment system of CVD with Chinese characteristics, and provide a reference for research and transformation in this field.

关键词

心血管疾病 / 中西医结合 / 人工智能 / 机器学习

Key words

Cardiovascular disease / Integrated traditional Chinese and Western medicine / Artificial intelligence / Machine learning

引用本文

引用格式 ▾
高山泉,薛亚军,佘飞,彭朝权. 人工智能在中西医结合防治心血管疾病中的应用研究进展[J]. 新医学, 2026, 57(7): 695-706 DOI:10.12464/j.issn.0253-9802.2026-0677

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参考文献

[1]

国家心血管病中心, 中国心血管健康与疾病报告编写组, 胡盛寿. 中国心血管健康与疾病报告2024概要[J]. 中国循环杂志, 2025, 40(6): 521-559. DOI: 10.3969/j.issn.1000-3614.2025.06.001.

[2]

National Center for Cardiovascular Diseases, The Writing Committee of the Report on Cardiovascular Health and Diseases in Chin. Report on cardiovascular health and diseases in China 2024: an updated summary[J]. Chin Circ J, 2025, 40(6): 521-559. DOI: 10.3969/j.issn.1000-3614.2025.06.001.

[3]

Fan Y, Yang Z, Wang L, et al. Traditional Chinese medicine for heart failure with preserved ejection fraction: clinical evidence and potential mechanisms[J]. Front Pharmacol, 2023, 14: 1154167. DOI: 10.3389/fphar.2023.1154167.

[4]

Yang Y, Li X, Chen G, et al. Traditional Chinese medicine compound (Tongxinluo) and clinical outcomes of patients with acute myocardial infarction: the CTS-AMI randomized clinical trial[J]. JAMA, 2023, 330(16): 1534-1545. DOI: 10.1001/jama.2023.19524.

[5]

Cheang I, Yao W, Zhou Y, et al. The traditional Chinese medicine Qiliqiangxin in heart failure with reduced ejection fraction: a randomized, double-blind, placebo-controlled trial[J]. Nat Med, 2024, 30(8): 2295-2302. DOI: 10.1038/s41591-024-03169-2.

[6]

Lüscher T F, et al. Artificial intelligence in cardiovascular medicine: clinical applications[J]. Eur Heart J, 2024, 45(40): 4291-4304. DOI: 10.1093/eurheartj/ehae465.

[7]

王宇立, 唐禹, 林佳成, 等 . 机器学习方法在中医证治规律研究中的应用进展及述评[J]. 中华中医药学刊, 2024, 42(10): 17-21. DOI: 10.13193/j.issn.1673-7717.2024.10.005.

[8]

Wang Y L, Tang Y, Lin J C, et al. Progress and review on application of machine learning methods in study of traditional Chinese medicine syndrome and treatment law[J]. Chin Arch Tradit Chin Med, 2024, 42(10): 17-21. DOI: 10.13193/j.issn.1673-7717.2024.10.005.

[9]

Haug C J, Drazen J M . Artificial intelligence and machine learning in clinical medicine, 2023[J]. N Engl J Med, 2023, 388(13): 1201-1208. DOI: 10.1056/nejmra2302038.

[10]

Layton A T . AI, machine learning, and ChatGPT in hypertension[J]. Hypertension, 2024, 81(4): 709-716. DOI: 10.1161/hypertensionaha.124.19468.

[11]

Theodore Armand T P, Nfor K A, Kim J I, et al. Applications of artificial intelligence, machine learning, and deep learning in nutrition: a systematic review[J]. Nutrients, 2024, 16(7): 1073. DOI: 10.3390/nu16071073.

[12]

Itchhaporia D. Artificial intelligence in cardiology[J]. Trends Cardiovasc Med, 2022, 32(1): 34-41. DOI: 10.1016/j.tcm.2020.11.007.

[13]

于荣博, 郭煊, 李发学, 等 . 人工智能在心电图自动分析中的应用及进展[J]. 新医学, 2026, 57(4): 350-360. DOI: 10.12464/j.issn.0253-9802.2025-0344.

[14]

Yu R B, Guo X, Li F X, et al. Application and progress of artificial intelligence in automated electrocardiogram analysis[J]. J New Med, 2026, 57(4): 350-360. DOI: 10.12464/j.issn.0253-9802.2025-0344.

[15]

Zhou B, Yang G, Shi Z, et al. Natural language processing for smart healthcare[J]. IEEE Rev Biomed Eng, 2024, 17: 4-18. DOI: 10.1109/RBME.2022.3210270.

[16]

黎超, 陈优美, 段亚妮, 等 . 生成式人工智能在生成影像学报告方面的表现评估[J]. 新医学, 2024, 55(11): 853-860. DOI: 10.3969/j.issn.0253-9802.2024.11.001.

[17]

Li C, Chen Y M, Duan Y N, et al. Evaluation of the performance of generative artificial intelligence in generating radiology reports[J]. J New Med, 2024, 55(11): 853-860. DOI: 10.3969/j.issn.0253-9802.2024.11.001.

[18]

刘子锋, 杨钦泰, 卢娅欣, 等 . 从数据治理到智能应用:医学“干实验室”建设的实践与思考[J]. 新医学, 2026, 57(4): 321-328. DOI: 10.12464/j.issn.0253-9802.2026-0165.

[19]

Liu Z F, Yang Q T, Lu Y X, et al. From data governance to intelligent applications: practice and reflection on building the medical “dry laboratory”[J]. J New Med, 2026, 57(4): 321-328. DOI: 10.12464/j.issn.0253-9802.2026-0165.

[20]

Yin L, Xue X, Pan S, et al. Artificial intelligence in Traditional Chinese Medicine: systematic insights from data mining, large language models, and multimodal fusion[J]. Acta Materia Med, 2025, 4(4): 674-697. DOI: 10.15212/amm-2025-0045.

[21]

Zhang K, Zhou H Y, Baptista-Hon D T, et al. Concepts and applications of digital twins in healthcare and medicine[J]. Patterns, 2024, 5(8): 101028. DOI: 10.1016/j.patter.2024.101028.

[22]

左仲琪, 王宇, 靳艳, 等 . 心血管疾病风险早期预警评估工具的范围综述[J]. 中国全科医学, 2024, 27(27): 3440-3445. DOI: 10.12114/j.issn.1007-9572.2023.0530.

[23]

Zuo Z Q, Wang Y, Jin Y, et al. Early warning assessment tools for cardiovascular disease risk: a scoping review[J]. Chin Gen Pract, 2024, 27(27): 3440-3445. DOI: 10.12114/j.issn.1007-9572.2023.0530.

[24]

朱晶晶, 张扬, 龚小会, 等 . 基于人工智能算法与中医体质类型的老年糖尿病患者合并心血管疾病预测模型[J]. 上海中医药杂志, 2025, 59(3): 1-6. DOI: 10.16305/j.1007-1334.2025.z20240801001.

[25]

Zhu J J, Zhang Y, Gong X H, et al. Prediction models for cardiovascular diseases in elderly diabetic patients based on artificial intelligence algorithms and traditional Chinese medicine constitution types[J]. Shanghai J Tradit Chin Med, 2025, 59(3): 1-6. DOI: 10.16305/j.1007-1334.2025.z20240801001.

[26]

钟霞, 赵天恩, 吕世盟, 等 . 基于中西医双维特征构建老年高血压轻度认知障碍机器学习预测模型[J]. 南京中医药大学学报, 2024, 40(12): 1366-1374. DOI: 10.14148/j.issn.1672-0482.2024.1366.

[27]

Zhong X, Zhao T E, Lyu S M, et al. Machine learning prediction model of mild cognitive impairment in elderly patients with hypertension based on bi-di-mensional features of Chinese and western medicine[J]. J Nanjing Univ Tradit Chin Med, 2024, 40(12): 1366-1374. DOI: 10.14148/j.issn.1672-0482.2024.1366.

[28]

Xing W, Shi Y, Wu C, et al. Predicting blood pressure from face videos using face diagnosis theory and deep neural networks technique[J]. Comput Biol Med, 2023, 164: 107112. DOI: 10.1016/j.compbiomed.2023.107112.

[29]

钟兰芳, 余新宇, 皮哲宇, 等 . 冠心病中医预警模型的研究现状与思考[J]. 中西医结合心脑血管病杂志, 2025, 23(23): 3594-3598. DOI: 10.12102/j.issn.1672-1349.2025.23.011.

[30]

Zhong L F, Yu X Y, Pi Z Y, et al. Research status and thinking on prediction models of coronary heart disease in Chinese medicine[J]. Chin J Integr Med Cardio/cerebrovascular Dis, 2025, 23(23): 3594-3598. DOI: 10.12102/j.issn.1672-1349.2025.23.011.

[31]

徐安迎, 王天舒, 杨涛, 等 . 基于多特征的中医体质辨识模型研究[J]. 数字中医药(英文版), 2024, 7(2): 108-119. DOI: 10.1016/j.dcmed.2024.09.002.

[32]

Xu A Y, Wang T S, Yang T, et al. Constitution identification model in traditional Chinese medicine based on multiple features[J]. Digit Chin Med, 2024, 7(2): 108-119. DOI: 10.1016/j.dcmed.2024.09.002.

[33]

吴紫陆, 白明华, 周玉美, 等 . 人工智能技术在中医体质辨识中的应用及展望[J]. 中国中医基础医学杂志, 2026, 32(4): 820-825. DOI: 10.19945/j.cnki.issn.1006-3250.2026.04.005.

[34]

Wu Z L, Bai M H, Zhou Y M, et al. Application and prospects of artificial intelligence technology in traditional Chinese medicine constitution identification[J]. J Basic Chin Med, 2026, 32(4): 820-825. DOI: 10.19945/j.cnki.issn.1006-3250.2026.04.005.

[35]

朱烔依, 汪佳琪, 张哲. 中医四诊诊断心血管疾病研究概述[J]. 中国现代药物应用, 2026, 20(3): 168-171. DOI: 10.14164/j.cnki.cn11-5581/r.2026.03.044.

[36]

Zhu T Y, Wang J Q, Zhang Z. An overview of research on diagnosing cardiovascular diseases using TCM four diagnostic methods[J]. Chin J Mod Drug Appl, 2026, 20(3): 168-171. DOI: 10.14164/j.cnki.cn11-5581/r.2026.03.044.

[37]

张莉莉, 张娴娴, 乔思竹, 等 . 脉诊客观化研究的文献计量与可视化分析[J]. 西部中医药, 2026, 39(1): 140-146. DOI: 10.12174/j.issn.2096-9600.2026.01.23.

[38]

Zhang L L, Zhang X X, Qiao S Z, et al. Objectification of pulse diagnosis: bibliometric and visual analysis[J]. West J Tradit Chin Med, 2026, 39(1): 140-146. DOI: 10.12174/j.issn.2096-9600.2026.01.23.

[39]

吕仪, 吴海妹, 燕海霞, 等 . 基于长短时记忆网络及智能调优算法优化的冠心病患者中医脉象识别研究[J]. 中华中医药杂志, 2025, 40(1): 77-82.

[40]

Lyu Y, Wu H M, Yan H X, et al. Study on pulse recognition of traditional Chinese medicine in patients with coronary heart disease based on long short-term memory and intelligent tuning algorithms[J]. China J Tradit Chin Med Pharm, 2025, 40(1): 77-82.

[41]

Qiao M, Yan Z, Tan C, et al. Integrating traditional Chinese pulse diagnosis with machine learning: novel approaches for pregnancy and coronary heart disease identification[J]. Sci Rep, 2025, 15: 35857. DOI: 10.1038/s41598-025-19780-3.

[42]

Lyu Y, Huang W Y, Wu H M, et al. A heart failure classification model from radial artery pulse wave using LSTM neural networks[J]. BMC Med Inform Decis Mak, 2025, 25(1): 318. DOI: 10.1186/s12911-025-03167-5.

[43]

朱易润. 面向房颤患者的脉象智能感知与识别系统研究[D]. 苏州: 苏州大学, 2023. DOI: 10.27351/d.cnki.gszhu.2023.002406.

[44]

Zhu Y R. Research on intelligent pulse sensing and recognition system for patients with atrial fibrillation[D]. Suzhou: Soochow University, 2023. DOI: 10.27351/d.cnki.gszhu.2023.002406.

[45]

汪佳琪, 朱炯依, 张哲. 中医舌诊客观化技术研究进展及其在冠心病研究中的应用[J]. 中国医药科学, 2025, 15(22): 57-60,92. DOI: 10.20116/j.issn2095-0616.2025.22.11.

[46]

Wang J Q, Zhu J Y, Zhang Z. Progress in objective techniques of traditional Chinese medicine tongue diagnosis and its application in coronary heart disease research[J]. China Med Pharm, 2025, 15(22): 57-60, 92. DOI: 10.20116/j.issn2095-0616.2025.22.11.

[47]

Jiatuo X U, Tao J I A N G, Shi L I U . Research status and prospect of tongue image diagnosis analysis based on machine learning[J]. Digit Chin Med, 2024, 7(1): 3-12. DOI: 10.1016/j.dcmed.2024.04.002.

[48]

Zhang Y Y, Wei D S, Zhang Y, et al. Quantitative research on tongue diagnosis in traditional Chinese medicine for obstructive coronary artery disease: a computational analysis based on multimodal feature fusion[J]. Digit Chin Med, 2025, 8(4): 443-454. DOI: 10.1016/j.dcmed.2025.12.001.

[49]

杨珺涵. 阻塞性冠心病舌脉多模态诊断模型的构建与评价研究[D]. 沈阳: 辽宁中医药大学, 2025. DOI: 10.27213/d.cnki.glnzc.2025.000067.

[50]

Yang J H. Research on the construction and evaluation of a multimodal diagnostic model based on tongue and pulse for obstructive coronary artery disease[D]. Shenyang: Liaoning University of Traditional Chinese medicine, 2025. DOI: 10.27213/d.cnki.glnzc.2025.000067.

[51]

张冀豫, 许家佗, 屠立平, 等 . 基于自适应权重多模态中西医数据融合方法的冠心病血管阻塞程度预测模型的构建与评价[J]. 数字中医药(英文版), 2025, 8(2): 163-173. DOI: 10.1016/j.dcmed.2025.05.005.

[52]

Zhang J Y, Xu J T, Tu L P, et al. Construction and evaluation of a predictive model for the degree of coronary artery occlusion based on adaptive weighted multi-modal fusion of traditional Chinese and western medicine data[J]. Digital Chinese Medicine (English version), 2025, 8(2): 163-173. DOI: 10.1016/j.dcmed.2025.05.005.

[53]

宋添力, 马婧, 李海霞, 等 . 基于中医目诊理论和白睛成像AI及光学技术分析高血压病患者目络特征及发病机制的关联性研究[J]. 中华中医药学刊, 2024, 42(12): 15-19. DOI: 10.13193/j.issn.1673-7717.2024.12.004.

[54]

Song T L, Ma J, Li H X, et al. Analyzing correlation between characteristics and pathogenesis of eye collateral in hypertensive patients based on theory of eye diagnosis in traditional Chinese medicine and white eye imaging AI and optical technology[J]. Chin Arch Tradit Chin Med, 2024, 42(12): 15-19. DOI: 10.13193/j.issn.1673-7717.2024.12.004.

[55]

邢维颖. 基于深度学习和中医面诊的血压预测模型构建[D]. 北京: 北京中医药大学, 2023. DOI: 10.26973/d.cnki.gbjzu.2023.000110.

[56]

Xing W Y. Construction of blood pressure prediction model based on deep learning and TCM facial diagnosis[D]. Beijing: Beijing University of Chinese Medicine, 2023. DOI: 10.26973/d.cnki.gbjzu.2023.000110.

[57]

陈浩然, 姜童, 郑一, 等 . 基于机器学习的冠心病稳定型心绞痛痰浊闭阻证诊断模型研究[J]. 中国中医药信息杂志, 2024, 31(12): 142-150. DOI: 10.19879/j.cnki.1005-5304.202407108.

[58]

Chen H R, Jiang T, Zheng Y, et al. Study on the diagnosis model of phlegm-dampness obstruction syndrome in patients with stable angina pectoris due to coronary heart disease based on machine learning[J]. Chin J Inf Tradit Chin Med, 2024, 31(12): 142-150. DOI: 10.19879/j.cnki.1005-5304.202407108.

[59]

殷悦. 基于机器学习的冠心病不稳定型心绞痛中医智能辨证模型构建研究[D]. 北京: 北京中医药大学, 2023. DOI: 10.26973/d.cnki.gbjzu.2023.000180.

[60]

Yin Y. Construction of an intelligent TCM syndrome differentiation model for unstable angina pectoris in coronary heart disease based on machine learning[D]. Beijing University of Chinese Medicine, 2023. DOI: 10.26973/d.cnki.gbjzu.2023.000180.

[61]

Liu J, Dan W, Liu X, et al. Development and validation of predictive model based on deep learning method for classification of dyslipidemia in Chinese medicine[J]. Health Inf Sci Syst, 2023, 11(1): 21. DOI: 10.1007/s13755-023-00215-0.

[62]

Zhang P, Zhang D, Zhou W, et al. Network pharmacology: towards the artificial intelligence-based precision traditional Chinese medicine[J]. Brief Bioinform, 2023, 25(1): bbad518. DOI: 10.1093/bib/bbad518.

[63]

Li X, Li X, Wang L, et al. Advancing traditional Chinese medicine research through network pharmacology: strategies for target identification, mechanism elucidation and innovative therapeutic applications[J]. Am J Chin Med, 2025, 53(7): 2021-2042. DOI: 10.1142/S0192415X25500752.

[64]

Luo Y, Mou Y, Li Z, et al. AI-driven identification of nutrition-modulated biomarkers and drug targets for cardiovascular therapeutic mechanisms[J]. Front Pharmacol, 2026, 17: 1793532. DOI: 10.3389/fphar.2026.1793532.

[65]

何睿阳, 李承悦, 宋坪, 等 . 数智技术在名老中医经验传承中的应用与思考[J]. 环球中医药, 2026, 19(3): 410-419. DOI: 10.3969/j.issn.1674-1749.2026.03.002.

[66]

He R Y, Li C Y, Song P, et al. Application and reflections on digital intelligence technologies in the inheritance of veteran TCM practitioners’ expertise[J]. Glob Tradit Chin Med, 2026, 19(3): 410-419. DOI: 10.3969/j.issn.1674-1749.2026.03.002.

[67]

朱永华. 基于知识图谱的中医药防治高血压经验挖掘及健康管理策略研究[D]. 南京: 南京中医药大学, 2025. DOI: 10.27253/d.cnki.gnjzu.2025.001088.

[68]

Zhu Y H. Knowledge graph-based mining of traditional Chinese medicine experience in the prevention and treatment of hypertension and health management strategies[D]. Nanjing: Nanjing University of Chinese Medicine, 2025. DOI: 10.27253/d.cnki.gnjzu.2025.001088.

[69]

钟远明. 基于数据挖掘的中医药治疗冠心病用药配伍研究[D]. 赣州: 江西理工大学, 2025. DOI: 10.27176/d.cnki.gnfyc.2025.000109.

[70]

Zhong M Y. Research on the drug compatibility in Traditional Chinese Medicine for treating coronary heart disease based on data mining[D]. Ganzhou: Jiangxi University of Science and Technology, 2025. DOI: 10.27176/d.cnki.gnfyc.2025.000109.

[71]

卢若竹. 基于数据挖掘邓悦教授对阵发性房颤和频发房性早搏用药规律及其核心处方网络药理学作用机制研究[D]. 长春: 长春中医药大学, 2023. DOI: 10.26980/d.cnki.gcczc.2023.000079.

[72]

Lu R Z. Data mining based on Professor Deng Yue's study on the pharmacological mechanism of action of medication pattern of paroxysmal atrial fibrillation and frequent premature atrial beats and its core prescription network pharmacology[D]. Changchun: Changchun University of Chinese Medicine, 2023. DOI: 10.26980/d.cnki.gcczc.2023.000079.

[73]

Teng Y, Li Y, Wang L, et al. Effectiveness and pharmacological mechanisms of Chinese herbal medicine for coronary heart disease complicated with heart failure[J]. J Ethnopharmacol, 2024, 322: 117605. DOI: 10.1016/j.jep.2023.117605.

[74]

Dong Q, Huang Y, Tao Z, et al. Discussion on the mechanism of Lingguizhugan Decoction in treating hypertension based on network pharmacology and molecular simulation technology[J]. J Biomol Struct Dyn, 2025, 43(4): 2159-2170. DOI: 10.1080/07391102.2023.2294172.

[75]

江启煜, 曾慧妍. 基于人工智能和组学数据驱动的中药潜在机制新型分析预测方法[J]. 中国组织工程研究, 2025, 29(35): 7552-7561. DOI: 10.12307/2025.968.

[76]

Jiang Q Y, Zeng H Y. A novel analysis and prediction method for potential mechanisms of Traditional Chinese Medicine based on artificial intelligence and omics data-driven approach[J]. CJTER, 2025, 29(35): 7552-7561. DOI: 10.12307/2025.968.

[77]

王晶爱. 基于古今特征融合与图卷积网络的药对配伍预测研究[D]. 北京: 中国中医科学院, 2025. DOI: 10.27658/d.cnki.gzzyy.2025.000223.

[78]

Wang J A. Research on herb pair compatibility prediction based on ancient and modern feature fusion and graph convolution network[D]. Beijin: China Academy of Chinese Medical Sciences, 2025. DOI: 10.27658/d.cnki.gzzyy.2025.000223.

[79]

Zhao M, Feng L, Li W . Network pharmacology and experimental verification: SanQi-DanShen treats coronary heart disease by inhibiting the PI3K/AKT signaling pathway[J]. Drug Des Devel Ther, 2024, 18: 4529-4550. DOI: 10.2147/DDDT.S480248.

[80]

郑蕊, 杨曜源, 陈昭, 等 . 构建以临床需求为导向的中西药联用安全性数智评价系统:临床困境、问题特征与方法路径[J]. 科学通报, 2026, 71: 4223-4231. DOI: 10.1360/CSB-2026-0084.

[81]

Zheng R, Yang Y Y, Chen Z, et al. A clinically-oriented intelligent digital evaluation system for safety evaluation of integrated traditional Chinese and western medicine: challenges and methodological pathways[J]. Chin Sci Bull, 2026, 71: 4223-4231. DOI: 10.1360/CSB-2026-0084.

[82]

石榴. 心力衰竭利尿剂抵抗中医优势人群“画像”构建及动态优化方案研究[D]. 北京: 北京中医药大学, 2024. DOI: 10.26973/d.cnki.gbjzu.2024.000070.

[83]

Shi L. Construction of "Portrait" for TCM advantageous population in heart failure with diuretic resistance and research on dynamic optimization scheme[D]. Beijing: Beijing University of Chinese Medicine, 2024. DOI: 10.26973/d.cnki.gbjzu.2024.000070.

[84]

Zhou J, Lou V, Zhao Y, et al. A Mechanistic Framework Integrating Renal QSP-PK-PD and Machine Learning for Baseline-Informed Stratification of Diuretic Resistance[J]. Aaps J, 2026, 28(4). DOI: 10.1208/s12248-026-01255-6.

[85]

于佳田, 周聪慧, 佟旭. 整合生物信息学与机器学习的冠心病早期诊断生物标志物筛选及中药治疗预测[J]. 中国中医基础医学杂志, 2026, 32(3): 510-517. DOI: 10.3969/j.issn.1006-3250.2026.03.008.

[86]

Yu J T, Zhou C H, Tong X. Screening of biomarkers for early diagnosis of coronary artery disease and prediction of Chinese Materia Medica treatment by integrating bioinformatics and machine learning[J]. Chin J Basic Med TCM, 2026, 32(3): 510-517. DOI: 10.3969/j.issn.1006-3250.2026.03.008.

[87]

贾思涵, 连妍洁, 尚菊菊, 等 . 基于生物信息学分析动脉粥样硬化铜死亡相关基因及调控中药预测[J]. 世界中西医结合杂志, 2025, 20(10): 1965-1977. DOI: 10.13935/j.cnki.sjzx.251007.

[88]

Jia S H, Lian Y J, Shang J J, et al. Bioinformatics analysis of cuproptosis-related genes and screening of Chinese Medicines for prevention and treatment in atherosclerosis[J]. World J Integr Tradit West Med, 2025, 20(10): 1965-1977. DOI: 10.13935/j.cnki.sjzx.251007.

[89]

乔连生, 李军, 谢兰, 等 . 基于靶向转录组、专家经验和人工智能研发守正创新中药的路径探索:以治疗慢性心力衰竭的中药新药研发为例[J]. 中医杂志, 2023, 64(3): 217-224. DOI: 10.13288/j.11-2166/r.2023.03.001.

[90]

Qiao L S, Li J, Xie L, et al. The exploration of a new approach for developing innovative Chinese herbal formulae by combining targeted transcriptome, expert experience and artificial intelligence: taking the development of anti-chronic heart failure innovative formula as an example[J]. J Tradit Chin Med, 2023, 64(3): 217-224. DOI: 10.13288/j.11-2166/r.2023.03.001.

[91]

母慧娟, 王一川. 人工智能在中药新药质量评价中的应用与思考[J]. 中国药事, 2024, 38(6): 644-652. DOI: 10.16153/j.1002-7777.2024.06.006.

[92]

Mu H J, Wang Y C. Application and reflection of artificial intelligence in quality evaluation of new Traditional Chinese Medicine[J]. Chinese Pharmaceutical Affairs, 2024, 38(6): 644-652. DOI: 10.16153/j.1002-7777.2024.06.006.

[93]

Ge T, Zou R, Bo J, et al. Machine learning prediction of myocardial ischaemia‒reperfusion injury: Clinical features and Qishen Yiqi dripping pills mechanism[J]. Phytomedicine, 2026, 150: 157590. DOI: 10.1016/j.phymed.2025.157590.

[94]

邢玉萍. 老年慢性心力衰竭患者中西医结合预后模型研究[D]. 济南: 山东中医药大学, 2024. DOI: 10.27282/d.cnki.gsdzu.2024.001125.

[95]

Xing Y P. Prognostic model study of combined Chinese and western medicine in elderly patients with chronic heart failure[D]. Jinan: Shandong University of Traditional Chinese Medicine, 2024. DOI: 10.27282/d.cnki.gsdzu.2024.001125.

[96]

陶诗怡, 于林童, 杨德爽, 等 . 冠心病PCI术后主要不良心血管事件风险中西医结合临床预测模型建立[J]. 中国中西医结合杂志, 2025, 45(2): 153-161. DOI: 10.7661/j.cjim.20241223.188.

[97]

Tao S Y, Yu L T, Yang D S, et al. Development of integrated Chinese and Western Medicine clinical prediction model for risk of major adverse cardiovascular events after percutaneous coronary intervention in patients with coronary heart disease[J]. Chin J Int Trad West Med, 2025, 45(2): 153-161. DOI: 10.7661/j.cjim.20241223.188.

[98]

刘雨婷. NOCAD不良心血管事件中西医多模态预测模型研究[D]. 沈阳: 辽宁中医药大学, 2025. DOI: 10.27213/d.cnki.glnzc.2025.000051.

[99]

Liu Y T. A Multi-modal predictive model integrating traditional Chinese and western medicine for adverse cardiovascular events in non-obstructive coronary artery disease[D]. Shenyang: Liaoning University Of Traditional Chinese Medicine, 2025. DOI: 10.27213/d.cnki.glnzc.2025.000051.

[100]

中华医学会心血管病学分会介入心脏病学组, 中国康复医学会心脏介入治疗与康复专业委员会, 国家心血管病中心专家委员会, 等 . 经皮冠状动脉介入治疗患者术后长期管理中国专家共识[J]. 中国循环杂志, 2026, 41( 1): 1-21. DOI: 10.3969/j.issn.1000-3614.2026.01.001.

[101]

Interventional Cardiology Group, Chinese Society of Cardiolgy, Chinese Academy Society of Cardiovascular Intervention and Rehabilitation, Chinese Association of Rehabilitation, Expert Committee of National Center for Cardiovascular Diseases, et al. Chinese expert consensus on long-term management following percutaneous coronary intervention in patients with coronary artery disease[J]. Chin Circ J, 2026, 41(1): 1-21. DOI: 10.3969/j.issn.1000-3614.2026.01.001.

[102]

侯小芬. 基于人工智能舌诊辨识系统的高血压病慢病管理系统的构建[D]. 合肥: 安徽中医药大学, 2024. DOI: 10.26922/d.cnki.ganzc.2024.000309.

[103]

Hou X F. Construction of chronic hypertension management system based on artificial intelligence tongue diagnosis identification system[D]. Hefei: Anhui University of Chinese Medicine, 2024. DOI: 10.26922/d.cnki.ganzc.2024.000309.

[104]

马凯文, 赵瑞祥, 孙艳秋, 等 . 面向心血管疾病的人工智能中医诊疗辅助系统的设计与实现[J]. 中华中医药学刊, 2026: 1-14.

[105]

Ma K W, Zhao R X, Sun Y Q, et al. Design and implementation of an artificial intelligence-based Traditional Chinese Medicine diagnostic and treatment assistance system for cardiovascular diseases[J]. Chin Arch Trad Chin Med, 2026: 1-14.

[106]

李洪峥, 王阶, 郭雨晨, 等 . 基于改良Transformer算法的冠心病证候要素诊断处方模型分析[J]. 中国实验方剂学杂志, 2023, 29(1): 148-154. DOI: 10.13422/j.cnki.syfjx.20221347.

[107]

Li H Z, Wang J, Guo Y C, et al. Research on diagnosis and prescription system of coronary heart disease with syndrome elements based on improved transformer algorithm[J]. Chin J Exp Trad Med Form, 2023, 29(1): 148-154. DOI: 10.13422/j.cnki.syfjx.20221347.

[108]

曾希娜, 田丽凤, 邱雄泉, 等 . 心脑血管疾病中成药合理用药AI模式的构建和效果评价[J]. 中国处方药, 2026, 24(4): 72-75. DOI: 10.3969/j.issn.1671-945X.2026.04.014.

[109]

Zeng X N, Tian L F, Qiu X Q, et al. Establishment and effect evaluation of AI model for rational use of Chinese patent medicines for cardiovascular and cerebrovascular diseases[J]. J Chin Pres Drug, 2026, 24(4): 72-75. DOI: 10.3969/j.issn.1671-945X.2026.04.014.

[110]

谭含璇, 林吉怡, 占平云, 等 . 人工智能在高血压管理中的发展、机遇和挑战[J]. 中华高血压杂志(中英文), 2024, 32(12): 1101-1105. DOI: 10.16439/j.issn.1673-7245.2024.12.001.

[111]

Tan H X, Lin J Y, Zhan P Y, et al. Development, opportunities and challenges of artificial intelligence in hypertension management[J]. Chin J Hypertens, 2024, 32(12): 1101-1105. DOI: 10.16439/j.issn.1673-7245.2024.12.001.

[112]

Dai Y, Shao X, Zhang J, et al. TCMChat: a generative large language model for traditional Chinese medicine[J]. Pharmacol Res, 2024, 210: 107530. DOI: 10.1016/j.phrs.2024.107530.

[113]

黄天爱, 徐刚, 杨华元, 等 . 生成式人工智能在中医药科研中的应用前景与问题思考[J]. 中国中医药信息杂志, 2025, 32(7): 180-186. DOI: 10.19879/j.cnki.1005-5304.202405298.

[114]

Huang T A, Xu G, Yang H Y, et al. Application prospects and issues of generative artificial intelligence in TCM research[J]. Chin J Inf Tradit Chin Med, 2025, 32(7): 180-186. DOI: 10.19879/j.cnki.1005-5304.202405298.

基金资助

国家中医药管理局监测统计中心中医药监测统计研究课题(2025JCTJC92)

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