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摘要
目的:设计一种能兼具全局感知与高分辨率特征保持能力的分割框架SSCU-UNet,以提升多器官CT与心脏MRI的分割性能。方法:提出SSCU-UNet分割框架,包含3个核心设计:(1)残差卷积下采样模块采用双路径结构,通过Conv-GELU-Conv主路径与步长卷积快捷路径融合,并结合层归一化以保留高分辨率空间特征。(2)SSFormer模块,位于每个Swin Transformer块中的窗口注意力和多层感知器之间,沿残差分支运行,以增强局部空间建模,同时通过空间位移注意力保持全局上下文推理。(3)内容感知注意力上采样模块根据输入特征自适应生成重建权重,以实现更精确的边界恢复。结果:在Synapse数据集上,SSCU-UNet的平均Dice相似系数为82.62%,较U-Net、TransUNet与Swin-UNet分别提升5.77%、5.14%和3.49%,Hausdorff距离降至18.79 mm,显著改善胆囊、胰腺、胃等形态复杂器官的边界精度。在ACDC数据集上,平均Dice相似系数达92.34%,优于多种基线模型。结论:SSCU-UNet通过整合残差卷积下采样、空间位移增强局部建模和内容感知上采样,有效平衡全局语义推理与细粒度结构恢复,在多器官分割任务中取得先进性能。
Abstract
Objective To design a segmentation framework, namely spatial shift-enhanced and content-aware upsampling UNet (SSCU-UNet), which balances global context awareness and high-resolution feature retention to improve performance in multi-organ CT and cardiac MRI segmentation tasks. Methods The proposed SSCU-UNet segmentation framework incorporated 3 key components. (1) A residual convolutional downsampling module adopted a dual-branch structure consisting of a Conv-GELU-Conv main branch and a strided-convolution shortcut branch, and coupled with layer normalization to retain high-resolution spatial information. (2) A SSFormer module was inserted between the window attention and multilayer perceptron of each Swin Transformer block, and operates along the residual branch to enhance local spatial modeling while maintaining global contextual reasoning via spatial shift attention. (3) A content-aware attention upsampling module was used to enable finer boundary restoration, which adaptively generates feature reconstruction weights according to input features. Results The proposed SSCU-UNet achieved an average Dice similarity coefficient of 82.62% on the Synapse dataset, which was 5.77%, 5.14%, and 3.49% higher than U-Net, TransUNet, and Swin-UNet, respectively, and reduced the Hausdorff distance to 18.79 mm, with particularly prominent performance improvements for anatomically complex organs including the gallbladder, pancreas, and stomach. On the ACDC dataset, the SSCU-UNet yielded an average Dice similarity coefficient of 92.34%, outperforming multiple baseline models. Conclusion By integrating residual convolutional downsampling, spatial shift-enhanced local modeling, and content-aware upsampling, the SSCU-UNet effectively balances global semantic reasoning with fine-grained structural reconstruction, and achieves state-of-the-art performance in multi-organ segmentation tasks.
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Key words
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金丰庆,周月娥,索国栋,杨建兰.
SSCU-UNet:融合空间位移与内容感知注意力的医学图像分割模型[J].
中国医学物理学杂志, 2026, 43(6): 787-797 DOI:10.3969/j.issn.1005-202X.2026.06.012
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基金资助
泉州市科技项目(2023N002S)